A new effective antiplasmodial compound: Nanoformulated pyrimethamine.

Pestehchian, Nader; Vafaei, Mohammad Reza; Nematolahy, Pardis; Varshosaz, Jaleh; Yousefi, Hossein Ali; Bide, Vahab Ziaei; Kalani, Hamed

Pestehchian, Nader; Vafaei, Mohammad Reza; Nematolahy, Pardis; Varshosaz, Jaleh; Yousefi, Hossein Ali; Bide, Vahab Ziaei; Kalani, Hamed.

Afiliação

Pestehchian N; Department of Parasitology and Mycology, School of Medicine and Infectious Diseases and Tropical Medicine Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Vafaei MR; Department of Parasitology and Mycology, School of Medicine and Infectious Diseases and Tropical Medicine Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Nematolahy P; Department of Pathology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Varshosaz J; Department of Pharmaceutics, School of Pharmacy and Novel Drug Delivery Systems Research Center, Isfahan University of Medical Sciences, Isfahan, Iran. Electronic address: varshosaz@pharm.mui.ac.ir.
Yousefi HA; Department of Parasitology and Mycology, School of Medicine and Infectious Diseases and Tropical Medicine Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Bide VZ; Department of Pharmaceutics, School of Pharmacy and Novel Drug Delivery Systems Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Kalani H; Infectious Diseases Research Center, Golestan University of Medical Sciences, Gorgan, Iran. Electronic address: hamed.kalani@yahoo.com.

J Glob Antimicrob Resist ; 20: 309-315, 2020 03.

Article em En | MEDLINE | ID: mdl-31404680

Assuntos

Antimaláricos/administração & dosagem; Malária/tratamento farmacológico; Parasitemia/tratamento farmacológico; Plasmodium berghei/efeitos dos fármacos; Poloxâmero/química; Pirimetamina/administração & dosagem; Animais; Antimaláricos/síntese química; Antimaláricos/química; Antimaláricos/farmacologia; Modelos Animais de Doenças; Composição de Medicamentos; Fígado/efeitos dos fármacos; Fígado/parasitologia; Masculino; Camundongos; Micelas; Nanopartículas; Tamanho da Partícula; Plasmodium berghei/patogenicidade; Pirimetamina/síntese química; Pirimetamina/química; Pirimetamina/farmacologia; Distribuição Aleatória; Baço/efeitos dos fármacos; Baço/parasitologia; Análise de Sobrevida; Resultado do Tratamento

Palavras-chave

Malaria; Nanomicelles; Plasmodium berghei; Poloxamer 407; Pyrimethamine

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Plasmodium berghei / Pirimetamina / Parasitemia / Poloxâmero / Malária / Antimaláricos Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google