Expanding the biological utility of bis-NHC gold(i) complexes through post synthetic carbamate conjugation.
Chem Commun (Camb)
; 55(71): 10627-10630, 2019 Aug 29.
Article
em En
| MEDLINE
| ID: mdl-31429450
ABSTRACT
We report the synthesis of a novel hydroxyl-functionalised heteroleptic bis-NHC gold(i) complex that permits conjugation to various amines via carbamate bond formation. The resulting derivatives were studied in vitro using cell proliferation assays and fluorescent microscopic imaging of human cancer cell lines.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Carbamatos
/
Complexos de Coordenação
/
Corantes Fluorescentes
/
Aminas
/
Ouro
/
Antineoplásicos
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article