A comparison of the acute effect of single doses of vigabatrin and sodium valproate on photosensitivity in epileptic patients.
Epilepsy Res
; 1(6): 339-46, 1987.
Article
em En
| MEDLINE
| ID: mdl-3143556
ABSTRACT
The acute effect of oral administration of a single dose of vigabatrin, a new antiepileptic drug which acts by irreversible enzyme-activated inhibition of the brain enzyme, GABA-aminotransferase, on the photoconvulsive response in patients with photosensitive epilepsy, was compared with that of the established antiepileptic drug, sodium valproate. Both drugs significantly suppressed the photoconvulsive response in 3 out of 6 subjects. This result was interpreted as further evidence of vigabatrin's potential value in the future treatment of patients with epilepsy.
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Base de dados:
MEDLINE
Assunto principal:
Vias Visuais
/
Ácido Valproico
/
Epilepsia
/
Aminocaproatos
/
Luz
Idioma:
En
Ano de publicação:
1987
Tipo de documento:
Article