Evolution of intron splicing towards optimized gene expression is based on various Cis- and Trans-molecular mechanisms.

Frumkin, Idan; Yofe, Ido; Bar-Ziv, Raz; Gurvich, Yonat; Lu, Yen-Yun; Voichek, Yoav; Towers, Ruth; Schirman, Dvir; Krebber, Heike; Pilpel, Yitzhak

Frumkin, Idan; Yofe, Ido; Bar-Ziv, Raz; Gurvich, Yonat; Lu, Yen-Yun; Voichek, Yoav; Towers, Ruth; Schirman, Dvir; Krebber, Heike; Pilpel, Yitzhak.

Afiliação

Frumkin I; Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel.
Yofe I; Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel.
Bar-Ziv R; Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel.
Gurvich Y; Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel.
Lu YY; Abteilung für Molekulare Genetik, Institut für Mikrobiologie und Genetik, Göttinger Zentrum für Molekulare Biowissenschaften (GZMB), Georg-August Universität Göttingen, Göttingen, Germany.
Voichek Y; Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel.
Towers R; Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel.
Schirman D; Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel.
Krebber H; Abteilung für Molekulare Genetik, Institut für Mikrobiologie und Genetik, Göttinger Zentrum für Molekulare Biowissenschaften (GZMB), Georg-August Universität Göttingen, Göttingen, Germany.
Pilpel Y; Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel.

PLoS Biol ; 17(8): e3000423, 2019 08.

Article em En | MEDLINE | ID: mdl-31442222

Assuntos

Adaptação Biológica/genética; Splicing de RNA/genética; Trans-Splicing/genética; Adaptação Biológica/fisiologia; Evolução Molecular; Expressão Gênica/genética; Regulação Fúngica da Expressão Gênica/genética; Íntrons/genética; Mutação; Precursores de RNA/metabolismo; RNA Mensageiro/metabolismo; Saccharomyces cerevisiae/genética; Proteínas de Saccharomyces cerevisiae/genética; Spliceossomos/metabolismo

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Adaptação Biológica / Splicing de RNA / Trans-Splicing Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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