Peritumoural CCL1 and CCL22 expressing cells in hepatocellular carcinomas shape the tumour immune infiltrate.

Wiedemann, Gabriela M; Röhrle, Natascha; Makeschin, Marie-Christine; Fesseler, Julia; Endres, Stefan; Mayr, Doris; Anz, David

Wiedemann, Gabriela M; Röhrle, Natascha; Makeschin, Marie-Christine; Fesseler, Julia; Endres, Stefan; Mayr, Doris; Anz, David.

Afiliação

Wiedemann GM; Center of Integrated Protein Science Munich (CIPS-M), Division of Clinical Pharmacology, Klinikum der Universität München, Munich, Germany; Department of Medicine II, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.
Röhrle N; Center of Integrated Protein Science Munich (CIPS-M), Division of Clinical Pharmacology, Klinikum der Universität München, Munich, Germany.
Makeschin MC; Pathologisches Institut, Medizinische Fakultät der Ludwig-Maximilians Universität München, Munich, Germany.
Fesseler J; Center of Integrated Protein Science Munich (CIPS-M), Division of Clinical Pharmacology, Klinikum der Universität München, Munich, Germany.
Endres S; Center of Integrated Protein Science Munich (CIPS-M), Division of Clinical Pharmacology, Klinikum der Universität München, Munich, Germany.
Mayr D; Pathologisches Institut, Medizinische Fakultät der Ludwig-Maximilians Universität München, Munich, Germany.
Anz D; Center of Integrated Protein Science Munich (CIPS-M), Division of Clinical Pharmacology, Klinikum der Universität München, Munich, Germany; Department of Medicine II, University Hospital, Ludwig-Maximilians-Universität München, Munich, Germany. Electronic address: d.anz@lmu.de.

Pathology ; 51(6): 586-592, 2019 Oct.

Article em En | MEDLINE | ID: mdl-31445808

Assuntos

Carcinoma Hepatocelular/metabolismo; Quimiocina CCL1/metabolismo; Quimiocina CCL22/metabolismo; Neoplasias Hepáticas/metabolismo; Linfócitos do Interstício Tumoral/metabolismo; Adulto; Idoso; Idoso de 80 Anos ou mais; Linfócitos T CD8-Positivos/metabolismo; Carcinoma Hepatocelular/patologia; Feminino; Fatores de Transcrição Forkhead/metabolismo; Humanos; Neoplasias Hepáticas/patologia; Linfócitos do Interstício Tumoral/patologia; Masculino; Pessoa de Meia-Idade; Linfócitos T Reguladores/metabolismo; Adulto Jovem

Palavras-chave

CCL1; CCL22; HCC; chemokines; regulatory T cell

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Linfócitos do Interstício Tumoral / Carcinoma Hepatocelular / Quimiocina CCL1 / Quimiocina CCL22 / Neoplasias Hepáticas Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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