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Concomitant targeting of Hedgehog signaling and MCL-1 synergistically induces cell death in Hedgehog-driven cancer cells.
Meister, Michael Torsten; Boedicker, Cathinka; Linder, Benedikt; Kögel, Donat; Klingebiel, Thomas; Fulda, Simone.
Afiliação
  • Meister MT; Institute for Experimental Cancer Research in Pediatrics, Goethe-University Frankfurt, Komturstr. 3a, 60528, Frankfurt, Germany; German Cancer Consortium (DKTK), Partner Site Frankfurt, Germany; German Cancer Research Center (DKFZ), Heidelberg, Germany; Division of Pediatric Hematology and Oncology,
  • Boedicker C; Institute for Experimental Cancer Research in Pediatrics, Goethe-University Frankfurt, Komturstr. 3a, 60528, Frankfurt, Germany; German Cancer Consortium (DKTK), Partner Site Frankfurt, Germany; German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Linder B; Experimental Neurosurgery, Neuroscience Center, Goethe-University Hospital, Frankfurt, Germany.
  • Kögel D; German Cancer Consortium (DKTK), Partner Site Frankfurt, Germany; Experimental Neurosurgery, Neuroscience Center, Goethe-University Hospital, Frankfurt, Germany.
  • Klingebiel T; German Cancer Consortium (DKTK), Partner Site Frankfurt, Germany; German Cancer Research Center (DKFZ), Heidelberg, Germany; Division of Pediatric Hematology and Oncology, Hospital for Children and Adolescents, Goethe-University, Frankfurt, Germany.
  • Fulda S; Institute for Experimental Cancer Research in Pediatrics, Goethe-University Frankfurt, Komturstr. 3a, 60528, Frankfurt, Germany; German Cancer Consortium (DKTK), Partner Site Frankfurt, Germany; German Cancer Research Center (DKFZ), Heidelberg, Germany. Electronic address: simone.fulda@kgu.de.
Cancer Lett ; 465: 1-11, 2019 Nov 28.
Article em En | MEDLINE | ID: mdl-31465840
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Piridinas / Pirimidinas / Sulfonamidas / Proteínas Hedgehog / Proteína de Sequência 1 de Leucemia de Células Mieloides / Indóis / Neoplasias Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Piridinas / Pirimidinas / Sulfonamidas / Proteínas Hedgehog / Proteína de Sequência 1 de Leucemia de Células Mieloides / Indóis / Neoplasias Idioma: En Ano de publicação: 2019 Tipo de documento: Article