Meta-Analysis Evaluating Outcomes of Surgical Left Atrial Appendage Occlusion During Cardiac Surgery.
Am J Cardiol
; 124(8): 1218-1225, 2019 10 15.
Article
em En
| MEDLINE
| ID: mdl-31474327
ABSTRACT
Surgical left atrial appendage occlusion (S-LAAO) has become a common procedure performed in patients undergoing cardiac surgery; however, evidence to support this procedure remains inconclusive. This meta-analysis aims to assess the efficacy of S-LAAO in terms of ischemic stroke, postoperative atrial fibrillation, and all-cause mortality. A thorough literature review was performed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement. We identified 10 relevant studies for our meta-analysis. It included 6,779 patients who underwent S-LAAO and 6,573 who did not undergo LAAO. In terms of ischemic stroke, the S-LAAO cohort had a lower events (pooled odds ratio [OR] 0.655 (0.518 to 0.829), pâ¯=â¯0.0004) compared with the non-LAAO cohort. S-LAAO cohort also had lower events of all-cause mortality (pooled OR 0.74 (95% confidence interval 0.55 to 0.99), pâ¯=â¯0.0408) when compared with the non-LAAO cohort. In regards to postoperative atrial fibrillation, there was no difference between the 2 groups (pooled OR 1.29 (95% confidence interval 0.81 to 2.06), pâ¯=â¯0.2752). In conclusion, S-LAAO was associated with lower events of ischemic stroke or systemic embolism and all-cause mortality when compared to the non-LAAO group.
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Base de dados:
MEDLINE
Assunto principal:
Fibrilação Atrial
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Isquemia Encefálica
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Avaliação de Resultados em Cuidados de Saúde
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Apêndice Atrial
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Dispositivo para Oclusão Septal
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Procedimentos Cirúrgicos Cardíacos
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article