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The structural basis of lipid scrambling and inactivation in the endoplasmic reticulum scramblase TMEM16K.
Bushell, Simon R; Pike, Ashley C W; Falzone, Maria E; Rorsman, Nils J G; Ta, Chau M; Corey, Robin A; Newport, Thomas D; Christianson, John C; Scofano, Lara F; Shintre, Chitra A; Tessitore, Annamaria; Chu, Amy; Wang, Qinrui; Shrestha, Leela; Mukhopadhyay, Shubhashish M M; Love, James D; Burgess-Brown, Nicola A; Sitsapesan, Rebecca; Stansfeld, Phillip J; Huiskonen, Juha T; Tammaro, Paolo; Accardi, Alessio; Carpenter, Elisabeth P.
Afiliação
  • Bushell SR; Structural Genomics Consortium, Nuffield Department of Medicine, University of Oxford, Old Road Campus Research Building, Roosevelt Drive, Oxford, OX3 7DQ, UK.
  • Pike ACW; Structural Genomics Consortium, Nuffield Department of Medicine, University of Oxford, Old Road Campus Research Building, Roosevelt Drive, Oxford, OX3 7DQ, UK.
  • Falzone ME; Department of Biochemistry, Weill Cornell Medical School, 1300 York Avenue, New York, NY, 10065, USA.
  • Rorsman NJG; Department of Pharmacology, University of Oxford, Mansfield Road, Oxford, OX1 3QT, UK.
  • Ta CM; OxSyBio, Atlas Building, Harwell Campus, Didcot, Oxfordshire, OX11 0QX, UK.
  • Corey RA; Department of Pharmacology, University of Oxford, Mansfield Road, Oxford, OX1 3QT, UK.
  • Newport TD; Department of Cardiology, Washington University in St. Louis, St. Louis, MO, 63110, USA.
  • Christianson JC; Department of Biochemistry, University of Oxford, South Parks Road, Oxford, OX1 3QT, UK.
  • Scofano LF; Department of Biochemistry, University of Oxford, South Parks Road, Oxford, OX1 3QT, UK.
  • Shintre CA; Oxford Nanopore Technologies, Oxford Science Park, Oxford, OX4 4DQ, UK.
  • Tessitore A; Nuffield Department of Rheumatology, Orthopaedics and Musculoskeletal Sciences, University of Oxford, Windmill Road, Oxford, OX3 7LD, UK.
  • Chu A; Department of Pharmacology, University of Oxford, Mansfield Road, Oxford, OX1 3QT, UK.
  • Wang Q; Structural Genomics Consortium, Nuffield Department of Medicine, University of Oxford, Old Road Campus Research Building, Roosevelt Drive, Oxford, OX3 7DQ, UK.
  • Shrestha L; Vertex Pharmaceuticals Ltd, Milton Park, Oxfordshire, OX14 4RW, UK.
  • Mukhopadhyay SMM; Structural Genomics Consortium, Nuffield Department of Medicine, University of Oxford, Old Road Campus Research Building, Roosevelt Drive, Oxford, OX3 7DQ, UK.
  • Love JD; Nuffield Division of Clinical Laboratory Sciences, Oxford University, Oxford, OX3 9DU, UK.
  • Burgess-Brown NA; Structural Genomics Consortium, Nuffield Department of Medicine, University of Oxford, Old Road Campus Research Building, Roosevelt Drive, Oxford, OX3 7DQ, UK.
  • Sitsapesan R; Department of Biochemistry, Oxford University, Oxford, OX1 3QT, UK.
  • Stansfeld PJ; Structural Genomics Consortium, Nuffield Department of Medicine, University of Oxford, Old Road Campus Research Building, Roosevelt Drive, Oxford, OX3 7DQ, UK.
  • Huiskonen JT; Department of Biochemistry, University of Oxford, South Parks Road, Oxford, OX1 3QT, UK.
  • Tammaro P; Structural Genomics Consortium, Nuffield Department of Medicine, University of Oxford, Old Road Campus Research Building, Roosevelt Drive, Oxford, OX3 7DQ, UK.
  • Accardi A; Structural Genomics Consortium, Nuffield Department of Medicine, University of Oxford, Old Road Campus Research Building, Roosevelt Drive, Oxford, OX3 7DQ, UK.
  • Carpenter EP; Department of Biochemistry, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY, 10461-1602, USA.
Nat Commun ; 10(1): 3956, 2019 09 02.
Article em En | MEDLINE | ID: mdl-31477691
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas de Transferência de Fosfolipídeos / Retículo Endoplasmático / Anoctaminas / Lipídeos Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas de Transferência de Fosfolipídeos / Retículo Endoplasmático / Anoctaminas / Lipídeos Idioma: En Ano de publicação: 2019 Tipo de documento: Article