[Successful lung transplantation after long-term ventilator and extracorporeal membrane oxygenation support in a patient with severe bronchiolitis obliterans following allogeneic bone marrow transplantation].
Rinsho Ketsueki
; 60(8): 920-923, 2019.
Article
em Ja
| MEDLINE
| ID: mdl-31484890
ABSTRACT
A 29-year-old man was diagnosed with acute myeloid leukemia at 20 years of age; he achieved a second complete remission at 22 years of age after an allogeneic unrelated bone marrow transplantation. After 14 months, he developed bronchiolitis obliterans (BO) due to chronic graft-versus-host disease. Home ventilator management was continuously performed for 3 years, but the patient required extracorporeal membrane oxygenation (ECMO) after progression to type 2 respiratory failure. A matched brain-dead lung donor was found after 5 months of intensive care management on ECMO, and bilateral lung transplantation was successfully performed. BO is a progressive refractory respiratory disease with poor prognosis. Careful management of infection, monitoring organ function, and lung transplantation at the appropriate time of initiation of mechanical ventilation or ECMO may save a patient's life. However, it is crucial to collaborate with higher education institutions or medical professionals in other departments.
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Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Bronquiolite Obliterante
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Oxigenação por Membrana Extracorpórea
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Transplante de Pulmão
Idioma:
Ja
Ano de publicação:
2019
Tipo de documento:
Article