Transcriptomic analysis reveals potential mechanisms of toxicity in a combined exposure to dibutyl phthalate and diisobutyl phthalate in zebrafish (Danio rerio) ovary.

Chen, Hui; Feng, Weiwei; Chen, Kun; Qiu, Xuchun; Xu, Hai; Mao, Guanghua; Zhao, Ting; Ding, Yangyang; Wu, Xiangyang

Chen, Hui; Feng, Weiwei; Chen, Kun; Qiu, Xuchun; Xu, Hai; Mao, Guanghua; Zhao, Ting; Ding, Yangyang; Wu, Xiangyang.

Afiliação

Chen H; School of the Environment and Safety Engineering, Jiangsu University, Zhenjiang 212013, People's Republic of China.
Feng W; School of the Environment and Safety Engineering, Jiangsu University, Zhenjiang 212013, People's Republic of China.
Chen K; School of the Environment and Safety Engineering, Jiangsu University, Zhenjiang 212013, People's Republic of China.
Qiu X; School of the Environment and Safety Engineering, Jiangsu University, Zhenjiang 212013, People's Republic of China.
Xu H; School of the Environment and Safety Engineering, Jiangsu University, Zhenjiang 212013, People's Republic of China.
Mao G; School of the Environment and Safety Engineering, Jiangsu University, Zhenjiang 212013, People's Republic of China.
Zhao T; School of the Chemistry and Chemical Engineering, Jiangsu University, Zhenjiang 212013, People's Republic of China.
Ding Y; School of the Environment and Safety Engineering, Jiangsu University, Zhenjiang 212013, People's Republic of China.
Wu X; School of the Environment and Safety Engineering, Jiangsu University, Zhenjiang 212013, People's Republic of China. Electronic address: wuxy@ujs.edu.cn.

Aquat Toxicol ; 216: 105290, 2019 Nov.

Article em En | MEDLINE | ID: mdl-31518775

Assuntos

Dibutilftalato/análogos & derivados; Dibutilftalato/toxicidade; Exposição Ambiental; Perfilação da Expressão Gênica; Ovário/metabolismo; Transcriptoma/genética; Peixe-Zebra/genética; Animais; Feminino; Regulação da Expressão Gênica/efeitos dos fármacos; Ontologia Genética; Hormônios Esteroides Gonadais/sangue; Ovário/efeitos dos fármacos; Ovário/patologia; Reprodutibilidade dos Testes; Reprodução/efeitos dos fármacos; Reprodução/genética; Poluentes Químicos da Água/toxicidade; Peixe-Zebra/sangue

Palavras-chave

Combined toxicity; Phthalate esters; Toxicity mechanism; Transcriptome; Zebrafish ovarian

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ovário / Peixe-Zebra / Perfilação da Expressão Gênica / Dibutilftalato / Exposição Ambiental / Transcriptoma Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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