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Development of novel multipotent compounds modulating endocannabinoid and dopaminergic systems.
Grillo, Alessandro; Chemi, Giulia; Brogi, Simone; Brindisi, Margherita; Relitti, Nicola; Fezza, Filomena; Fazio, Domenico; Castelletti, Laura; Perdona, Elisabetta; Wong, Andrea; Lamponi, Stefania; Pecorelli, Alessandra; Benedusi, Mascia; Fantacci, Manuela; Valoti, Massimo; Valacchi, Giuseppe; Micheli, Fabrizio; Novellino, Ettore; Campiani, Giuseppe; Butini, Stefania; Maccarrone, Mauro; Gemma, Sandra.
Afiliação
  • Grillo A; Department of Biotechnology, Chemistry and Pharmacy, DoE Department of Excellence 2018-2022, University of Siena, via Aldo Moro 2, 53100, Siena, Italy.
  • Chemi G; Department of Biotechnology, Chemistry and Pharmacy, DoE Department of Excellence 2018-2022, University of Siena, via Aldo Moro 2, 53100, Siena, Italy.
  • Brogi S; Department of Pharmacy, University of Pisa, via Bonanno 6, 56126, Pisa, Italy.
  • Brindisi M; Department of Pharmacy, University of Napoli Federico II, DoE Department of Excellence 2018-2022, Via D. Montesano 49, 80131, Napoli, Italy.
  • Relitti N; Department of Biotechnology, Chemistry and Pharmacy, DoE Department of Excellence 2018-2022, University of Siena, via Aldo Moro 2, 53100, Siena, Italy.
  • Fezza F; Department of Experimental Medicine, University of Rome Tor Vergata, via Montpellier 1, 00133, Rome, Italy.
  • Fazio D; Faculty of Biosciences and Technology for Food Agriculture and Environment, University of Teramo, via R. Balzarini 1, 64100, Teramo, Italy; Department of Medicine, Campus Bio-Medico University of Rome, Via Alvaro del Portillo 21, 00128, Rome, Italy.
  • Castelletti L; Aptuit (Verona) Srl, an Evotec Company, Via Alessandro Fleming, 4, 37135, Verona, Italy.
  • Perdona E; Aptuit (Verona) Srl, an Evotec Company, Via Alessandro Fleming, 4, 37135, Verona, Italy.
  • Wong A; Aptuit (Verona) Srl, an Evotec Company, Via Alessandro Fleming, 4, 37135, Verona, Italy.
  • Lamponi S; Department of Biotechnology, Chemistry and Pharmacy, DoE Department of Excellence 2018-2022, University of Siena, via Aldo Moro 2, 53100, Siena, Italy.
  • Pecorelli A; NC State University, Plants for Human Health Institute, 600 Laureate Way, Kannapolis, NC, 28081, USA.
  • Benedusi M; Department of Biomedical and Specialist Surgical Sciences, University of Ferrara, Via Borsari 46, 44121, Ferrara, Italy.
  • Fantacci M; Department of Life Sciences, University of Siena, via Aldo Moro 2, 53100, Siena, Italy.
  • Valoti M; Department of Life Sciences, University of Siena, via Aldo Moro 2, 53100, Siena, Italy.
  • Valacchi G; NC State University, Plants for Human Health Institute, 600 Laureate Way, Kannapolis, NC, 28081, USA; Department of Biomedical and Specialist Surgical Sciences, University of Ferrara, Via Borsari 46, 44121, Ferrara, Italy; Department of Food and Nutrition, Kyung Hee University, Seoul, South Korea.
  • Micheli F; Aptuit (Verona) Srl, an Evotec Company, Via Alessandro Fleming, 4, 37135, Verona, Italy.
  • Novellino E; Department of Pharmacy, University of Napoli Federico II, DoE Department of Excellence 2018-2022, Via D. Montesano 49, 80131, Napoli, Italy.
  • Campiani G; Department of Biotechnology, Chemistry and Pharmacy, DoE Department of Excellence 2018-2022, University of Siena, via Aldo Moro 2, 53100, Siena, Italy. Electronic address: campiani@unisi.it.
  • Butini S; Department of Biotechnology, Chemistry and Pharmacy, DoE Department of Excellence 2018-2022, University of Siena, via Aldo Moro 2, 53100, Siena, Italy. Electronic address: butini3@unisi.it.
  • Maccarrone M; Department of Medicine, Campus Bio-Medico University of Rome, Via Alvaro del Portillo 21, 00128, Rome, Italy; European Center for Brain Research, Santa Lucia Foundation IRCCS, Via del Fosso di Fiorano snc, 00176, Rome, Italy.
  • Gemma S; Department of Biotechnology, Chemistry and Pharmacy, DoE Department of Excellence 2018-2022, University of Siena, via Aldo Moro 2, 53100, Siena, Italy.
Eur J Med Chem ; 183: 111674, 2019 Dec 01.
Article em En | MEDLINE | ID: mdl-31518969
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Dopamina / Endocanabinoides / Amidoidrolases Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Dopamina / Endocanabinoides / Amidoidrolases Idioma: En Ano de publicação: 2019 Tipo de documento: Article