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Benzothiazole-based compounds as potent endothelial lipase inhibitors.
Meng, Wei; Adam, Leonard P; Behnia, Kamelia; Zhao, Lei; Yang, Richard; Kopcho, Lisa M; Locke, Gregory A; Taylor, David S; Yin, Xiaohong; Wexler, Ruth R; Finlay, Heather.
Afiliação
  • Meng W; Department of Discovery Chemistry, Bristol-Myers Squibb, Research and Development, PO Box 5400, Princeton, NJ 08543-5400, United States. Electronic address: wei.meng@bms.com.
  • Adam LP; Department of Cardiovascular Diseases, Bristol-Myers Squibb, Research and Development, PO Box 5400, Princeton, NJ 08543-5400, United States.
  • Behnia K; Department of Pharmaceutical Candidate Optimization, Bristol-Myers Squibb, Research and Development, PO Box 5400, Princeton, NJ 08543-5400, United States.
  • Zhao L; Department of Cardiovascular Diseases, Bristol-Myers Squibb, Research and Development, PO Box 5400, Princeton, NJ 08543-5400, United States.
  • Yang R; Department of Cardiovascular Diseases, Bristol-Myers Squibb, Research and Development, PO Box 5400, Princeton, NJ 08543-5400, United States.
  • Kopcho LM; Department of Pharmaceutical Candidate Optimization, Bristol-Myers Squibb, Research and Development, PO Box 5400, Princeton, NJ 08543-5400, United States.
  • Locke GA; Department of Pharmaceutical Candidate Optimization, Bristol-Myers Squibb, Research and Development, PO Box 5400, Princeton, NJ 08543-5400, United States.
  • Taylor DS; Department of Cardiovascular Diseases, Bristol-Myers Squibb, Research and Development, PO Box 5400, Princeton, NJ 08543-5400, United States.
  • Yin X; Department of Cardiovascular Diseases, Bristol-Myers Squibb, Research and Development, PO Box 5400, Princeton, NJ 08543-5400, United States.
  • Wexler RR; Department of Discovery Chemistry, Bristol-Myers Squibb, Research and Development, PO Box 5400, Princeton, NJ 08543-5400, United States.
  • Finlay H; Department of Discovery Chemistry, Bristol-Myers Squibb, Research and Development, PO Box 5400, Princeton, NJ 08543-5400, United States.
Bioorg Med Chem Lett ; 29(20): 126673, 2019 10 15.
Article em En | MEDLINE | ID: mdl-31519373
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doenças Cardiovasculares / Inibidores Enzimáticos / Benzotiazóis / Lipase Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doenças Cardiovasculares / Inibidores Enzimáticos / Benzotiazóis / Lipase Idioma: En Ano de publicação: 2019 Tipo de documento: Article