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Utilizing the Combination of Binding Kinetics and Micro-Pharmacokinetics Link in Vitro α-Glucosidase Inhibition to in Vivo Target Occupancy.
Wang, Guopeng; Ji, Yanhua; Li, Xueyan; Wang, Qian; Gong, Hang; Wang, Baoshun; Liu, Yang; Pan, Yanli.
Afiliação
  • Wang G; Zhongcai Health (Beijing) Biological Technology Development Co., Ltd., Beijing 101500, China. binglelly@163.com.
  • Ji Y; School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, China. 20170931834@bucm.edu.cn.
  • Li X; School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, China. 20180935003@bucm.edu.cn.
  • Wang Q; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, 100191, China. qian.wang@bjmu.edu.cn.
  • Gong H; School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, China. gonghang0620@163.com.
  • Wang B; School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, China. 20170223038@bucm.edu.cn.
  • Liu Y; School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, China. liuyang@bucm.edu.cn.
  • Pan Y; Institute of Information on Traditional Chinese Medicine China Academy of Chinese Medical Sciences, Beijing 100700, China. panyl@mail.cintcm.ac.cn.
Biomolecules ; 9(9)2019 09 16.
Article em En | MEDLINE | ID: mdl-31527517
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Saccharomyces cerevisiae / Alfa-Glucosidases / Inibidores de Glicosídeo Hidrolases Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Saccharomyces cerevisiae / Alfa-Glucosidases / Inibidores de Glicosídeo Hidrolases Idioma: En Ano de publicação: 2019 Tipo de documento: Article