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Neutralization-guided design of HIV-1 envelope trimers with high affinity for the unmutated common ancestor of CH235 lineage CD4bs broadly neutralizing antibodies.
LaBranche, Celia C; Henderson, Rory; Hsu, Allen; Behrens, Shay; Chen, Xuejun; Zhou, Tongqing; Wiehe, Kevin; Saunders, Kevin O; Alam, S Munir; Bonsignori, Mattia; Borgnia, Mario J; Sattentau, Quentin J; Eaton, Amanda; Greene, Kelli; Gao, Hongmei; Liao, Hua-Xin; Williams, Wilton B; Peacock, James; Tang, Haili; Perez, Lautaro G; Edwards, Robert J; Kepler, Thomas B; Korber, Bette T; Kwong, Peter D; Mascola, John R; Acharya, Priyamvada; Haynes, Barton F; Montefiori, David C.
Afiliação
  • LaBranche CC; Department of Surgery, Duke University Medical Center, Durham, NC, United States of America.
  • Henderson R; Duke Human Vaccine Institute, Duke University Medical Center, Durham, NC, United States of America.
  • Hsu A; Genome Integrity and Structural Biology Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, NC, United States of America.
  • Behrens S; Department of Surgery, Duke University Medical Center, Durham, NC, United States of America.
  • Chen X; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America.
  • Zhou T; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America.
  • Wiehe K; Duke Human Vaccine Institute, Duke University Medical Center, Durham, NC, United States of America.
  • Saunders KO; Department of Medicine, Duke University Medical Center, Durham, NC, United States of America.
  • Alam SM; Department of Surgery, Duke University Medical Center, Durham, NC, United States of America.
  • Bonsignori M; Duke Human Vaccine Institute, Duke University Medical Center, Durham, NC, United States of America.
  • Borgnia MJ; Duke Human Vaccine Institute, Duke University Medical Center, Durham, NC, United States of America.
  • Sattentau QJ; Department of Medicine, Duke University Medical Center, Durham, NC, United States of America.
  • Eaton A; Duke Human Vaccine Institute, Duke University Medical Center, Durham, NC, United States of America.
  • Greene K; Department of Medicine, Duke University Medical Center, Durham, NC, United States of America.
  • Gao H; Genome Integrity and Structural Biology Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, NC, United States of America.
  • Liao HX; The Sir William Dunn School of Pathology, University of Oxford, Oxford, United Kingdom.
  • Williams WB; Department of Surgery, Duke University Medical Center, Durham, NC, United States of America.
  • Peacock J; Department of Surgery, Duke University Medical Center, Durham, NC, United States of America.
  • Tang H; Department of Surgery, Duke University Medical Center, Durham, NC, United States of America.
  • Perez LG; Duke Human Vaccine Institute, Duke University Medical Center, Durham, NC, United States of America.
  • Edwards RJ; Department of Medicine, Duke University Medical Center, Durham, NC, United States of America.
  • Kepler TB; Duke Human Vaccine Institute, Duke University Medical Center, Durham, NC, United States of America.
  • Korber BT; Department of Medicine, Duke University Medical Center, Durham, NC, United States of America.
  • Kwong PD; Duke Human Vaccine Institute, Duke University Medical Center, Durham, NC, United States of America.
  • Mascola JR; Department of Medicine, Duke University Medical Center, Durham, NC, United States of America.
  • Acharya P; Department of Surgery, Duke University Medical Center, Durham, NC, United States of America.
  • Haynes BF; Department of Surgery, Duke University Medical Center, Durham, NC, United States of America.
  • Montefiori DC; Duke Human Vaccine Institute, Duke University Medical Center, Durham, NC, United States of America.
PLoS Pathog ; 15(9): e1008026, 2019 09.
Article em En | MEDLINE | ID: mdl-31527908
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Anticorpos Anti-HIV / HIV-1 / Vacinas contra a AIDS / Produtos do Gene env do Vírus da Imunodeficiência Humana / Anticorpos Amplamente Neutralizantes Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Anticorpos Anti-HIV / HIV-1 / Vacinas contra a AIDS / Produtos do Gene env do Vírus da Imunodeficiência Humana / Anticorpos Amplamente Neutralizantes Idioma: En Ano de publicação: 2019 Tipo de documento: Article