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Single-Cell RNA Sequencing of hESC-Derived 3D Retinal Organoids Reveals Novel Genes Regulating RPC Commitment in Early Human Retinogenesis.
Mao, Xiying; An, Qin; Xi, Huiyu; Yang, Xian-Jie; Zhang, Xiangmei; Yuan, Songtao; Wang, Jinmei; Hu, Youjin; Liu, Qinghuai; Fan, Guoping.
Afiliação
  • Mao X; Department of Ophthalmology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China.
  • An Q; Department of Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, 695 Charles Young Drive South, Los Angeles, CA 90095, USA.
  • Xi H; Department of Ophthalmology, Xuzhou First People's Hospital of Xuzhou Medical University, Xuzhou Eye Research Institute, Xuzhou 221002, China.
  • Yang XJ; Stein Eye Institute, Molecular Biology Institute, University of California, Los Angeles, CA 90095, USA.
  • Zhang X; Stein Eye Institute, Molecular Biology Institute, University of California, Los Angeles, CA 90095, USA.
  • Yuan S; Department of Ophthalmology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China.
  • Wang J; Institute of Regenerative Medicine and International Lab of Ocular Stem Cells at Shanghai East Hospital, School of Life Science &Technology, Tongji University, Shanghai 200092, China.
  • Hu Y; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, China. Electronic address: huyoujin@gzzoc.com.
  • Liu Q; Department of Ophthalmology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China. Electronic address: liuqh@njmu.edu.cn.
  • Fan G; Department of Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, 695 Charles Young Drive South, Los Angeles, CA 90095, USA. Electronic address: gfan@mednet.ucla.edu.
Stem Cell Reports ; 13(4): 747-760, 2019 10 08.
Article em En | MEDLINE | ID: mdl-31543471
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Retina / Organoides / Regulação da Expressão Gênica no Desenvolvimento / Organogênese / Células-Tronco Embrionárias Humanas Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Retina / Organoides / Regulação da Expressão Gênica no Desenvolvimento / Organogênese / Células-Tronco Embrionárias Humanas Idioma: En Ano de publicação: 2019 Tipo de documento: Article