A mathematical model demonstrating the role of interstitial fluid flow on the clearance and accumulation of amyloid ß in the brain.

Chen, C Y; Tseng, Y H; Ward, J P

Chen, C Y; Tseng, Y H; Ward, J P.

Afiliação

Chen CY; Department of Applied Mathematics, National University of Kaohsiung, Kaohsiung, Taiwan. Electronic address: aprilchen@nuk.edu.tw.
Tseng YH; Department of Applied Mathematics, National University of Kaohsiung, Kaohsiung, Taiwan.
Ward JP; School of Mathematical Sciences, Loughborough University, Loughborough, UK.

Math Biosci ; 317: 108258, 2019 11.

Article em En | MEDLINE | ID: mdl-31562868

Assuntos

Doença de Alzheimer/metabolismo; Peptídeos beta-Amiloides/metabolismo; Encéfalo/metabolismo; Líquido Extracelular/metabolismo; Modelos Biológicos; Placa Amiloide/metabolismo; Doença de Alzheimer/líquido cefalorraquidiano; Humanos

Palavras-chave

Advection; Alzheimer's disease; Amyloid ß; Brain; Interstitial fluid; Mathematical model; Plaque formation

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Encéfalo / Peptídeos beta-Amiloides / Placa Amiloide / Líquido Extracelular / Doença de Alzheimer / Modelos Biológicos Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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