C9ORF72 protein function and immune dysregulation in amyotrophic lateral sclerosis.

Lai, Jesse D; Ichida, Justin K

Lai, Jesse D; Ichida, Justin K.

Afiliação

Lai JD; Department of Stem Cell Biology and Regenerative Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA; Department of Neuroscience, Amgen Inc., Cambridge, MA, USA.
Ichida JK; Department of Stem Cell Biology and Regenerative Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA; Eli and Edythe Broad CIRM Center for Regenerative Medicine and Stem Cell Research at USC, Los Angeles, CA, USA; Zilkha Neurogenetic Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA. Electronic address: ichida@usc.edu.

Neurosci Lett ; 713: 134523, 2019 11 20.

Article em En | MEDLINE | ID: mdl-31568865

Assuntos

Esclerose Lateral Amiotrófica/imunologia; Esclerose Lateral Amiotrófica/fisiopatologia; Proteína C9orf72/imunologia; Proteína C9orf72/fisiologia; Degeneração Neural/fisiopatologia; Animais; Proteína C9orf72/genética; Expansão das Repetições de DNA; Humanos

Palavras-chave

Amyotrophic lateral sclerosis; C9ORF72; Immunology; Neurodegeneration; Proteostasis

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteína C9orf72 / Esclerose Lateral Amiotrófica / Degeneração Neural Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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