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Effect of Selepressin vs Placebo on Ventilator- and Vasopressor-Free Days in Patients With Septic Shock: The SEPSIS-ACT Randomized Clinical Trial.
Laterre, Pierre-Francois; Berry, Scott M; Blemings, Allan; Carlsen, Jan E; François, Bruno; Graves, Todd; Jacobsen, Karsten; Lewis, Roger J; Opal, Steven M; Perner, Anders; Pickkers, Peter; Russell, James A; Windeløv, Nis A; Yealy, Donald M; Asfar, Pierre; Bestle, Morten H; Muller, Grégoire; Bruel, Cédric; Brulé, Noëlle; Decruyenaere, Johan; Dive, Alain-Michel; Dugernier, Thierry; Krell, Kenneth; Lefrant, Jean-Yves; Megarbane, Bruno; Mercier, Emmanuelle; Mira, Jean-Paul; Quenot, Jean-Pierre; Rasmussen, Bodil Steen; Thorsen-Meyer, Hans-Christian; Vander Laenen, Margot; Vang, Marianne Lauridsen; Vignon, Philippe; Vinatier, Isabelle; Wichmann, Sine; Wittebole, Xavier; Kjølbye, Anne Louise; Angus, Derek C.
Afiliação
  • Laterre PF; Department of Critical Care Medicine, St. Luc University Hospital, Université Catholique de Louvain, Brussels, Belgium.
  • Berry SM; Berry Consultants LLC, Austin, Texas.
  • Blemings A; Ferring Pharmaceuticals A/S, Copenhagen, Denmark.
  • Carlsen JE; StraDevo A/S, Kongens Lyngby, Denmark.
  • François B; Medical-Surgical Intensive Care Unit, Inserm CIC1435, Dupuytren Teaching Hospital, Limoges, France.
  • Graves T; Berry Consultants LLC, Austin, Texas.
  • Jacobsen K; Ferring Pharmaceuticals A/S, Copenhagen, Denmark.
  • Lewis RJ; Berry Consultants LLC, Austin, Texas.
  • Opal SM; Department of Emergency Medicine, Harbor-UCLA Medical Center, Torrance, California.
  • Perner A; Los Angeles Biomedical Research Institute, Torrance, California.
  • Pickkers P; Department of Emergency Medicine, David Geffen School of Medicine at UCLA, Los Angeles, California.
  • Russell JA; Division of Infectious Diseases, Alpert Medical School of Brown University, Providence, Rhode Island.
  • Windeløv NA; Department of Intensive Care, Rigshospitalet, Copenhagen, Denmark.
  • Yealy DM; Department of Intensive Care Medicine, Radboud University Medical Center, Nijmegen, the Netherlands.
  • Asfar P; Center for Heart Lung Innovation and the Division of Critical Care Medicine, St. Paul's Hospital, University of British Columbia, Vancouver, Canada.
  • Bestle MH; Ferring Pharmaceuticals A/S, Copenhagen, Denmark.
  • Muller G; Department of Emergency Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
  • Bruel C; Centre Hospitalier Universitaire d'Angers, Angers, France.
  • Brulé N; Nordsjaellands Hospital in Hilleroed, Copenhagen, Denmark.
  • Decruyenaere J; Centre Hospitalier Régional, Hopital de La Source, Orléans, France.
  • Dive AM; Fondation Hôpital Saint Joseph. Paris, France.
  • Dugernier T; Medical Intensive Care Unit, Nantes University Hospital, Nantes, France.
  • Krell K; Ghent University Hospital, Ghent, Belgium.
  • Lefrant JY; CHU UCL Manur, Mont-Godinne, Yvoir, Belgium.
  • Megarbane B; Clinique Saint-Pierre, Ottignies, Belgium.
  • Mercier E; Eastern Idaho Regional Medical Center, Idaho Falls.
  • Mira JP; Centre Hospitalier Universitaire de Nîmes, Nîmes, France.
  • Quenot JP; Lariboisière Hospital, Paris-Diderot University, INSERM UMRS-1144, Paris, France.
  • Rasmussen BS; Centre Hospitalier Régional et Universitaire de Tours, Tours, France.
  • Thorsen-Meyer HC; Hopital Cochin, Paris, France.
  • Vander Laenen M; Centre Hospitalier Régional et Universitaire de Dijon, Dijon, France.
  • Vang ML; Aalborg Universitetshospital, Aalborg, Denmark.
  • Vignon P; Department of Intensive Care, Rigshospitalet, Copenhagen, Denmark.
  • Vinatier I; Ziekenhuis Oost-Limburg, Genk, Belgium.
  • Wichmann S; Randers Regions Hospital, Randers, Denmark.
  • Wittebole X; Medical-Surgical Intensive Care Unit, Inserm CIC1435, Dupuytren Teaching Hospital, Limoges, France.
  • Kjølbye AL; Centre Hospitalier Departemental de Vendee, La Roche sur Yon, France.
  • Angus DC; Bispebjerg Hospital, Copenhagen, Denmark.
JAMA ; 322(15): 1476-1485, 2019 Oct 15.
Article em En | MEDLINE | ID: mdl-31577035
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2019 Tipo de documento: Article