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Safety, Tolerability, and Pharmacokinetics of the Mineralocorticoid Receptor Modulator AZD9977 in Healthy Men: A Phase I Multiple Ascending Dose Study.
Whittaker, Andrew; Kragh, Åsa M; Hartleib-Geschwindner, Judith; Albayaty, Muna; Backlund, Anna; Greasley, Peter J; Heijer, Maria; Kjaer, Magnus; Forte, Pablo; Unwin, Robert; Wernevik, Linda; Ericsson, Hans.
Afiliação
  • Whittaker A; Research and Early Development, Cardiovascular, Renal, and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
  • Kragh ÅM; Clinical Pharmacology, ADME and AI, Clinical Pharmacology & Safety Sciences, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
  • Hartleib-Geschwindner J; Research and Early Development, Cardiovascular, Renal, and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
  • Albayaty M; Early Phase Clinical Unit, PAREXEL, Harrow, UK.
  • Backlund A; Research and Early Development, Cardiovascular, Renal, and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
  • Greasley PJ; Research and Early Development, Cardiovascular, Renal, and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
  • Heijer M; Clinical Pharmacology Biologics and Bioanalysis, Clinical Pharmacology and Safety Sciences, R&D, AstraZeneca, Gothenburg, Sweden.
  • Kjaer M; Early Biometrics and Statistical Innovation, Data Science and AI, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
  • Forte P; Early Phase Clinical Unit, PAREXEL, Harrow, UK.
  • Unwin R; Research and Early Development, Cardiovascular, Renal, and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
  • Wernevik L; Research and Early Development, Cardiovascular, Renal, and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
  • Ericsson H; Clinical Pharmacology, ADME and AI, Clinical Pharmacology & Safety Sciences, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
Clin Transl Sci ; 13(2): 275-283, 2020 03.
Article em En | MEDLINE | ID: mdl-31584739
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Oxazinas / Benzoatos / Receptores de Mineralocorticoides / Antagonistas de Receptores de Mineralocorticoides / Hiperpotassemia Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Oxazinas / Benzoatos / Receptores de Mineralocorticoides / Antagonistas de Receptores de Mineralocorticoides / Hiperpotassemia Idioma: En Ano de publicação: 2020 Tipo de documento: Article