Impact of antipsychotic medication on IL-6/STAT3 signaling axis in peripheral blood mononuclear cells of drug-naive schizophrenia patients.

Subbanna, Manjula; Shivakumar, Venkataram; Venugopal, Deepthi; Narayanaswamy, Janardhanan C; Berk, Michael; Varambally, Shivarama; Venkatasubramanian, Ganesan; Debnath, Monojit

Subbanna, Manjula; Shivakumar, Venkataram; Venugopal, Deepthi; Narayanaswamy, Janardhanan C; Berk, Michael; Varambally, Shivarama; Venkatasubramanian, Ganesan; Debnath, Monojit.

Afiliação

Subbanna M; Department of Human Genetics, National Institute of Mental Health and Neurosciences, Bangalore, India.
Shivakumar V; Translational Psychiatry Laboratory, Neurobiology Research Centre, National Institute of Mental Health and Neurosciences, Bangalore, India.
Venugopal D; Translational Psychiatry Laboratory, Neurobiology Research Centre, National Institute of Mental Health and Neurosciences, Bangalore, India.
Narayanaswamy JC; Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore, India.
Berk M; Department of Human Genetics, National Institute of Mental Health and Neurosciences, Bangalore, India.
Varambally S; Translational Psychiatry Laboratory, Neurobiology Research Centre, National Institute of Mental Health and Neurosciences, Bangalore, India.
Venkatasubramanian G; Translational Psychiatry Laboratory, Neurobiology Research Centre, National Institute of Mental Health and Neurosciences, Bangalore, India.
Debnath M; Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore, India.

Psychiatry Clin Neurosci ; 74(1): 64-69, 2020 Jan.

Article em En | MEDLINE | ID: mdl-31587436

Assuntos

Antipsicóticos/farmacologia; Expressão Gênica/efeitos dos fármacos; Interleucina-6; Fator de Transcrição STAT3/efeitos dos fármacos; Esquizofrenia/sangue; Esquizofrenia/tratamento farmacológico; Esquizofrenia/fisiopatologia; Transdução de Sinais/efeitos dos fármacos; Células Th17/efeitos dos fármacos; Adulto; Feminino; Seguimentos; Humanos; Masculino; Resultado do Tratamento; Adulto Jovem

Palavras-chave

STAT3; Th17 pathway; antipsychotic treatment; inflammation; schizophrenia

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Esquizofrenia / Antipsicóticos / Transdução de Sinais / Expressão Gênica / Interleucina-6 / Fator de Transcrição STAT3 / Células Th17 Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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