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Prekallikrein inhibits innate immune signaling in the lung and impairs host defense during pneumosepsis in mice.
Ding, Chao; Scicluna, Brendon P; Stroo, Ingrid; Yang, Jack; Roelofs, Joris Jth; de Boer, Onno J; de Vos, Alex F; Nürnberg, Peter; Revenko, Alexey S; Crosby, Jeff; Van't Veer, Cornelis; van der Poll, Tom.
Afiliação
  • Ding C; Department of Gastric Surgery, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, PR China.
  • Scicluna BP; Center of Experimental & Molecular Medicine, Amsterdam University Medical Centers, location Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
  • Stroo I; Center of Experimental & Molecular Medicine, Amsterdam University Medical Centers, location Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
  • Yang J; Department of Clinical Epidemiology and Biostatistics, Amsterdam University Medical Centers, location Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
  • Roelofs JJ; Center of Experimental & Molecular Medicine, Amsterdam University Medical Centers, location Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
  • de Boer OJ; Center of Experimental & Molecular Medicine, Amsterdam University Medical Centers, location Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
  • de Vos AF; Department of Pathology, Amsterdam University Medical Centers, location Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
  • Nürnberg P; Department of Pathology, Amsterdam University Medical Centers, location Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
  • Revenko AS; Center of Experimental & Molecular Medicine, Amsterdam University Medical Centers, location Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
  • Crosby J; Cologne Center for Genomics (CCG), University of Cologne, Cologne, Germany.
  • Van't Veer C; Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany.
  • van der Poll T; Drug Discovery, Ionis Pharmaceuticals, Inc, Carlsbad, CA, USA.
J Pathol ; 250(1): 95-106, 2020 01.
Article em En | MEDLINE | ID: mdl-31595971

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Infecções por Klebsiella / Pré-Calicreína / Sepse / Pneumonia Bacteriana / Imunidade Inata / Klebsiella pneumoniae / Pulmão Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Infecções por Klebsiella / Pré-Calicreína / Sepse / Pneumonia Bacteriana / Imunidade Inata / Klebsiella pneumoniae / Pulmão Idioma: En Ano de publicação: 2020 Tipo de documento: Article