A multichannel system integrating molecularly imprinted conductive polymers for ultrasensitive voltammetric determination of four steroid hormones in urine.
Mikrochim Acta
; 186(11): 695, 2019 10 14.
Article
em En
| MEDLINE
| ID: mdl-31612312
ABSTRACT
This work reports on a modularized electrochemical method for the determination of the hormones cortisol, progesterone, testosterone and 17ß-estradiol in urine. These hormones were employed as templates when generating molecular imprints from aniline and metanilic acid by electropolymerization on the surface of screen-printed electrodes. The electrically conductive imprint was characterized by SEM, AFM and cyclic voltammetry. A four-channel system was then established to enable simultaneous determination of the hormones by cyclic voltammetry. The detection limits for cortisol, progesterone, testosterone and 17ß-estradiol are as low as 2, 2.5, 10 and 9 ag·mL-1 (for S/N = 3). Graphical abstract A four-channel system was established to enable simultaneous determination of 4 steroid hormones by cyclic voltammetry and by using moleculalry imprinted polymers.
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Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Polímeros
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Progesterona
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Testosterona
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Hidrocortisona
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Estradiol
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Técnicas Eletroquímicas
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article