Disease related single point mutations alter the global dynamics of a tetratricopeptide (TPR) &#945;-solenoid domain.

Llabrés, Salomé; Tsenkov, Maxim I; MacGowan, Stuart A; Barton, Geoffrey J; Zachariae, Ulrich

Disease related single point mutations alter the global dynamics of a tetratricopeptide (TPR) α-solenoid domain.

Llabrés, Salomé; Tsenkov, Maxim I; MacGowan, Stuart A; Barton, Geoffrey J; Zachariae, Ulrich.

Afiliação

Llabrés S; Computational Biology, School of Life Sciences, University of Dundee, Dundee, UK. Electronic address: salome.llabres@gmail.com.
Tsenkov MI; Computational Biology, School of Life Sciences, University of Dundee, Dundee, UK.
MacGowan SA; Computational Biology, School of Life Sciences, University of Dundee, Dundee, UK.
Barton GJ; Computational Biology, School of Life Sciences, University of Dundee, Dundee, UK.
Zachariae U; Computational Biology, School of Life Sciences, University of Dundee, Dundee, UK; Physics, School of Science and Engineering, University of Dundee, Dundee, UK. Electronic address: u.zachariae@dundee.ac.uk.

J Struct Biol ; 209(1): 107405, 2020 01 01.

Article em En | MEDLINE | ID: mdl-31628985

Assuntos

Deficiência Intelectual/genética; N-Acetilglucosaminiltransferases/química; N-Acetilglucosaminiltransferases/genética; Mutação Puntual; Humanos; Simulação de Dinâmica Molecular; N-Acetilglucosaminiltransferases/metabolismo; Conformação Proteica; Domínios Proteicos; Repetições de Tetratricopeptídeos

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Mutação Puntual / N-Acetilglucosaminiltransferases / Deficiência Intelectual Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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