Gut bacteria characteristic of the infant microbiota down-regulate inflammatory transcriptional responses in HT-29â¯cells.
Anaerobe
; 61: 102112, 2020 Feb.
Article
em En
| MEDLINE
| ID: mdl-31629806
ABSTRACT
Immuno-modulatory effects of infant gut bacteria were tested on poly(IC) stimulated HT-29 intestinal epithelial cells. Blautia producta, Bacteroides vulgatus, Bacteroides fragilis and Bacteroides thetaiotaomicron decreased transcription of poly(IC)-induced inflammatory genes. Modulation of basal level and poly(IC)-induced IL-8 secretion varied between bacterial species, and between heat treated and non-heat treated bacterial cells.
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Base de dados:
MEDLINE
Assunto principal:
Bactérias
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Transcrição Gênica
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Regulação da Expressão Gênica
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Microbioma Gastrointestinal
Idioma:
En
Ano de publicação:
2020
Tipo de documento:
Article