Evaluation of the Impact of Sarcopenia in Patients with Acute Mesenteric Ischemia.
Ann Vasc Surg
; 63: 170-178.e1, 2020 Feb.
Article
em En
| MEDLINE
| ID: mdl-31629853
ABSTRACT
BACKGROUND:
Sarcopenia has been identified as a prognostic factor in several diseases. The aim of this study was to investigate the impact of sarcopenia in patients with acute mesenteric ischemia.METHODS:
Consecutive patients admitted for acute mesenteric ischemia were retrospectively included at the University Hospital of Nice. Sarcopenia was assessed by the measurement of total psoas area normalized for height (TPA/H) on CT-scan and was defined as a TPA/H inferior to the lowest sex-specific quartile. The management of the patients and the 30-day outcomes were compared between sarcopenic and nonsarcopenic patients. Correlations between the TPA/H and biological characteristics were investigated.RESULTS:
Among the 80 patients included, the lowest quartile of TPA/H that defined sarcopenia was 406.1 mm2/m2 for men and 307 mm2/m2 for women. The rate of revascularization or the need of intestinal resection did not significantly differ between sarcopenic and nonsarcopenic patients (10.5% vs. 26.2%, P = 0.214 and 26.3% vs. 47.5%, P = 0.118 respectively). The 30-day mortality did not significantly differ between the two groups (63.2% vs. 47.5%, P = 0.297). The TPA/H was significantly negatively correlated with the neutrophil, thrombocyte, and monocyte counts (r = -0.283; -0.288, -0.225, P < 0.05) and positively correlated with the hemoglobin concentration and the glomerular filtration rate (r = 0.368; 0.261, P < 0.05).CONCLUSIONS:
Further studies on longer follow-up period would be of interest to fully understand the prognostic value of sarcopenia in patients with acute mesenteric ischemia.
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Músculos Psoas
/
Sarcopenia
/
Isquemia Mesentérica
/
Oclusão Vascular Mesentérica
Idioma:
En
Ano de publicação:
2020
Tipo de documento:
Article