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Age-related hyperinsulinemia leads to insulin resistance in neurons and cell-cycle-induced senescence.
Chow, Hei-Man; Shi, Meng; Cheng, Aifang; Gao, Yuehong; Chen, Guimiao; Song, Xuan; So, Raphaella Wai Lam; Zhang, Jie; Herrup, Karl.
Afiliação
  • Chow HM; School of Life Sciences, The Chinese University of Hong Kong, Sha Tin, Hong Kong. heimanchow@cuhk.edu.hk.
  • Shi M; Division of Life Science, Hong Kong University of Science and Technology, Kowloon, Hong Kong. heimanchow@cuhk.edu.hk.
  • Cheng A; The State Key Laboratory of Molecular Neuroscience, Hong Kong University of Science and Technology, Kowloon, Hong Kong. heimanchow@cuhk.edu.hk.
  • Gao Y; Fujian Provincial Key Laboratory of Neuroscience Disease and Aging Research, Institute of Neuroscience, College of Medicine, Xiamen University, Xiamen, People's Republic of China.
  • Chen G; Division of Life Science, Hong Kong University of Science and Technology, Kowloon, Hong Kong.
  • Song X; The State Key Laboratory of Molecular Neuroscience, Hong Kong University of Science and Technology, Kowloon, Hong Kong.
  • So RWL; Fujian Provincial Key Laboratory of Neuroscience Disease and Aging Research, Institute of Neuroscience, College of Medicine, Xiamen University, Xiamen, People's Republic of China.
  • Zhang J; Fujian Provincial Key Laboratory of Neuroscience Disease and Aging Research, Institute of Neuroscience, College of Medicine, Xiamen University, Xiamen, People's Republic of China.
  • Herrup K; Division of Life Science, Hong Kong University of Science and Technology, Kowloon, Hong Kong.
Nat Neurosci ; 22(11): 1806-1819, 2019 11.
Article em En | MEDLINE | ID: mdl-31636448

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Envelhecimento / Resistência à Insulina / Ciclo Celular / Senescência Celular / Hiperinsulinismo / Neurônios Idioma: En Ano de publicação: 2019 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Envelhecimento / Resistência à Insulina / Ciclo Celular / Senescência Celular / Hiperinsulinismo / Neurônios Idioma: En Ano de publicação: 2019 Tipo de documento: Article