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Influence of social cognition as a mediator between cognitive reserve and psychosocial functioning in patients with first episode psychosis.
González-Ortega, I; González-Pinto, A; Alberich, S; Echeburúa, E; Bernardo, M; Cabrera, B; Amoretti, S; Lobo, A; Arango, C; Corripio, I; Vieta, E; de la Serna, E; Rodriguez-Jimenez, R; Segarra, R; López-Ilundain, J M; Sánchez-Torres, A M; Cuesta, M J; Zorrilla, I; López, P; Bioque, M; Mezquida, G; Barcones, F; De-la-Cámara, C; Parellada, M; Espliego, A; Alonso-Solís, A; Grasa, E M; Varo, C; Montejo, L; Castro-Fornieles, J; Baeza, I; Dompablo, M; Torio, I; Zabala, A; Eguiluz, J I; Moreno-Izco, L; Sanjuan, J; Guirado, R; Cáceres, I; Garnier, P; Contreras, F; Bobes, J; Al-Halabí, S; Usall, J; Butjosa, A; Sarró, S; Landin-Romero, R; Ibáñez, A; Selva, G.
Afiliação
  • González-Ortega I; Centre for Biomedical Research in the Mental Health Network (CIBERSAM), Madrid, Spain.
  • González-Pinto A; Department of Psychiatry, Araba University Hospital, Bioaraba Research Institute, Vitoria, Spain.
  • Alberich S; Department of Neurosciences, University of the Basque Country, Bizkaia, Spain.
  • Echeburúa E; The National Distance Education University (UNED), Vitoria, Spain.
  • Bernardo M; Centre for Biomedical Research in the Mental Health Network (CIBERSAM), Madrid, Spain.
  • Cabrera B; Department of Psychiatry, Araba University Hospital, Bioaraba Research Institute, Vitoria, Spain.
  • Amoretti S; Department of Neurosciences, University of the Basque Country, Bizkaia, Spain.
  • Lobo A; Centre for Biomedical Research in the Mental Health Network (CIBERSAM), Madrid, Spain.
  • Arango C; Department of Psychiatry, Araba University Hospital, Bioaraba Research Institute, Vitoria, Spain.
  • Corripio I; Department of Neurosciences, University of the Basque Country, Bizkaia, Spain.
  • Vieta E; The National Distance Education University (UNED), Vitoria, Spain.
  • de la Serna E; Centre for Biomedical Research in the Mental Health Network (CIBERSAM), Madrid, Spain.
  • Rodriguez-Jimenez R; Department of Personality, Assessment and Psychological Treatment, University of the Basque Country, San Sebastián, Spain.
  • Segarra R; Centre for Biomedical Research in the Mental Health Network (CIBERSAM), Madrid, Spain.
  • López-Ilundain JM; Barcelona Clinic Schizophrenia Unit, Neuroscience Institute, Hospital Clinic of Barcelona, Barcelona, Spain.
  • Sánchez-Torres AM; Centre for Biomedical Research in the Mental Health Network (CIBERSAM), Madrid, Spain.
  • Cuesta MJ; Barcelona Clinic Schizophrenia Unit, Neuroscience Institute, Hospital Clinic of Barcelona, Barcelona, Spain.
  • Zorrilla I; Barcelona Clinic Schizophrenia Unit, Neuroscience Institute, Hospital Clinic of Barcelona, Barcelona, Spain.
  • López P; Centre for Biomedical Research in the Mental Health Network (CIBERSAM), Madrid, Spain.
  • Bioque M; Department of Medicine and Psychiatry, University of Zaragoza, Aragon Institute for Health Sciences (IIS Aragón), Zaragoza, Spain.
  • Mezquida G; Centre for Biomedical Research in the Mental Health Network (CIBERSAM), Madrid, Spain.
  • Barcones F; Child and Adolescent Psychiatry Department, Gregorio Marañón General University Hospital, School of Medicine, Universidad Complutense, IiSGM, Madrid, Spain.
  • De-la-Cámara C; Centre for Biomedical Research in the Mental Health Network (CIBERSAM), Madrid, Spain.
  • Parellada M; Department of Psychiatry, Institut d'Investigació Biomèdica-Sant Pau (IIB-SANT PAU), Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona (UAB), Barcelona, Spain.
  • Espliego A; Centre for Biomedical Research in the Mental Health Network (CIBERSAM), Madrid, Spain.
  • Alonso-Solís A; Bipolar Disorders Unit, Hospital Clinic, University of Barcelona, IDIBAPS, Barcelona, Spain.
  • Grasa EM; Centre for Biomedical Research in the Mental Health Network (CIBERSAM), Madrid, Spain.
  • Varo C; Child and Adolescent Psychiatry Service, Hospital Clinic of Barcelona, Barcelona, Spain.
  • Montejo L; Centre for Biomedical Research in the Mental Health Network (CIBERSAM), Madrid, Spain.
  • Castro-Fornieles J; 12 de Octubre Hospital Research Institute (i+12), Madrid, Spain.
  • Baeza I; Centre for Biomedical Research in the Mental Health Network (CIBERSAM), Madrid, Spain.
  • Dompablo M; Department of Neurosciences, University of the Basque Country, Cruces University Hospital, Biocruces Bizkaia Health Research Institute, Vizcaya, Spain.
  • Torio I; Department of Psychiatry, Navarre Hospital Complex, IdiSNA, Navarre Institute for Health Research, Pamplona, Spain.
  • Zabala A; Department of Psychiatry, Navarre Hospital Complex, IdiSNA, Navarre Institute for Health Research, Pamplona, Spain.
  • Eguiluz JI; Department of Psychiatry, Navarre Hospital Complex, IdiSNA, Navarre Institute for Health Research, Pamplona, Spain.
  • Sanjuan J; Centre for Biomedical Research in the Mental Health Network (CIBERSAM), Madrid, Spain.
  • Guirado R; Department of Psychiatry, Araba University Hospital, Bioaraba Research Institute, Vitoria, Spain.
  • Cáceres I; Department of Neurosciences, University of the Basque Country, Bizkaia, Spain.
  • Garnier P; Centre for Biomedical Research in the Mental Health Network (CIBERSAM), Madrid, Spain.
  • Contreras F; Department of Psychiatry, Araba University Hospital, Bioaraba Research Institute, Vitoria, Spain.
  • Bobes J; Department of Neurosciences, University of the Basque Country, Bizkaia, Spain.
  • Al-Halabí S; Centre for Biomedical Research in the Mental Health Network (CIBERSAM), Madrid, Spain.
  • Usall J; Barcelona Clinic Schizophrenia Unit, Neuroscience Institute, Hospital Clinic of Barcelona, Barcelona, Spain.
  • Butjosa A; Centre for Biomedical Research in the Mental Health Network (CIBERSAM), Madrid, Spain.
  • Sarró S; Barcelona Clinic Schizophrenia Unit, Neuroscience Institute, Hospital Clinic of Barcelona, Barcelona, Spain.
  • Landin-Romero R; Department of Medicine and Psychiatry, University of Zaragoza, Aragon Institute for Health Sciences (IIS Aragón), Zaragoza, Spain.
  • Ibáñez A; Department of Family Medicine, Hospital Universitario Miguel Servet, Zaragoza, Spain.
  • Selva G; Centre for Biomedical Research in the Mental Health Network (CIBERSAM), Madrid, Spain.
Psychol Med ; 50(16): 2702-2710, 2020 12.
Article em En | MEDLINE | ID: mdl-31637990
ABSTRACT

BACKGROUND:

Social cognition has been associated with functional outcome in patients with first episode psychosis (FEP). Social cognition has also been associated with neurocognition and cognitive reserve. Although cognitive reserve, neurocognitive functioning, social cognition, and functional outcome are related, the direction of their associations is not clear. Therefore, the main aim of this study was to analyze the influence of social cognition as a mediator between cognitive reserve and cognitive domains on functioning in FEP both at baseline and at 2 years.

METHODS:

The sample of the study was composed of 282 FEP patients followed up for 2 years. To analyze whether social cognition mediates the influence of cognitive reserve and cognitive domains on functioning, a path analysis was performed. The statistical significance of any mediation effects was evaluated by bootstrap analysis.

RESULTS:

At baseline, as neither cognitive reserve nor the cognitive domains studied were related to functioning, the conditions for mediation were not satisfied. Nevertheless, at 2 years of follow-up, social cognition acted as a mediator between cognitive reserve and functioning. Likewise, social cognition was a mediator between verbal memory and functional outcome. The results of the bootstrap analysis confirmed these significant mediations (95% bootstrapped CI (-10.215 to -0.337) and (-4.731 to -0.605) respectively).

CONCLUSIONS:

Cognitive reserve and neurocognition are related to functioning, and social cognition mediates in this relationship.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transtornos Psicóticos / Reserva Cognitiva / Cognição Social / Funcionamento Psicossocial Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transtornos Psicóticos / Reserva Cognitiva / Cognição Social / Funcionamento Psicossocial Idioma: En Ano de publicação: 2020 Tipo de documento: Article