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EWS-FLI1-mediated tenascin-C expression promotes tumour progression by targeting MALAT1 through integrin α5ß1-mediated YAP activation in Ewing sarcoma.
He, Shaohui; Huang, Quan; Hu, Jinbo; Li, Lei; Xiao, Yanbin; Yu, Hongyu; Han, Zhitao; Wang, Ting; Zhou, Wang; Wei, Haifeng; Xiao, Jianru.
Afiliação
  • He S; Spinal Tumor Center, Department of Orthopaedic Oncology, Changzheng Hospital, Second Military Medical University, Shanghai, 200003, P. R. China.
  • Huang Q; Spinal Tumor Center, Department of Orthopaedic Oncology, Changzheng Hospital, Second Military Medical University, Shanghai, 200003, P. R. China.
  • Hu J; Spinal Tumor Center, Department of Orthopaedic Oncology, Changzheng Hospital, Second Military Medical University, Shanghai, 200003, P. R. China.
  • Li L; Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences, School of Life Sciences, East China Normal University, Shanghai, 200241, P. R. China.
  • Xiao Y; Department of Orthopaedics, Musculoskeletal Tumor Center of Yunnan Province, the Third Affiliated Hospital of Kunming Medical University, Kunming Medical University, Kunming, 650106, Yunnan, P. R. China.
  • Yu H; Department of Pathology, Changzheng Hospital, Second Military Medical University, Shanghai, 200003, P. R. China.
  • Han Z; School of Medicine and Life Sciences, Nanjing University of Chinese Medicine, Nanjing, 210023, Jiangsu, P. R. China.
  • Wang T; Spinal Tumor Center, Department of Orthopaedic Oncology, Changzheng Hospital, Second Military Medical University, Shanghai, 200003, P. R. China.
  • Zhou W; Spinal Tumor Center, Department of Orthopaedic Oncology, Changzheng Hospital, Second Military Medical University, Shanghai, 200003, P. R. China. brilliant212@163.com.
  • Wei H; School of Medicine, Tsinghua University, Beijing, 100084, P. R. China. brilliant212@163.com.
  • Xiao J; Spinal Tumor Center, Department of Orthopaedic Oncology, Changzheng Hospital, Second Military Medical University, Shanghai, 200003, P. R. China. weihfspine@163.com.
Br J Cancer ; 121(11): 922-933, 2019 11.
Article em En | MEDLINE | ID: mdl-31649319
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sarcoma de Ewing / Fatores de Transcrição / Proteínas de Fusão Oncogênica / Proteínas de Ciclo Celular / Tenascina / Proteína EWS de Ligação a RNA / Integrina alfa5beta1 / Proteína Proto-Oncogênica c-fli-1 / RNA Longo não Codificante / Carcinogênese Idioma: En Ano de publicação: 2019 Tipo de documento: Article
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sarcoma de Ewing / Fatores de Transcrição / Proteínas de Fusão Oncogênica / Proteínas de Ciclo Celular / Tenascina / Proteína EWS de Ligação a RNA / Integrina alfa5beta1 / Proteína Proto-Oncogênica c-fli-1 / RNA Longo não Codificante / Carcinogênese Idioma: En Ano de publicação: 2019 Tipo de documento: Article