The metabolic fate of two new psychoactive substances - 2-aminoindane and N-methyl-2-aminoindane - studied in vitro and in vivo to support drug testing.

Manier, Sascha K; Felske, Christina; Eckstein, Niels; Meyer, Markus R

Manier, Sascha K; Felske, Christina; Eckstein, Niels; Meyer, Markus R.

Afiliação

Manier SK; Department of Experimental and Clinical Toxicology, Institute of Experimental and Clinical Pharmacology and Toxicology, Saarland University, Center for Molecular Signaling (PZMS), Homburg, Germany.
Felske C; Department of Experimental and Clinical Toxicology, Institute of Experimental and Clinical Pharmacology and Toxicology, Saarland University, Center for Molecular Signaling (PZMS), Homburg, Germany.
Eckstein N; Applied Pharmacy, University of Applied Sciences Kaiserslautern, Pirmasens, Germany.
Meyer MR; Applied Pharmacy, University of Applied Sciences Kaiserslautern, Pirmasens, Germany.

Drug Test Anal ; 12(1): 145-151, 2020 Jan.

Article em En | MEDLINE | ID: mdl-31667988

Assuntos

Drogas Desenhadas/metabolismo; Indanos/metabolismo; Microssomos Hepáticos/metabolismo; Psicotrópicos/metabolismo; Animais; Drogas Desenhadas/farmacocinética; Humanos; Indanos/urina; Espectrometria de Massas; Redes e Vias Metabólicas; Metilação; Psicotrópicos/urina; Ratos; Detecção do Abuso de Substâncias

Palavras-chave

LC−HRMS/MS; NPS; aminoindanes; in vitro; in vivo

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Psicotrópicos / Microssomos Hepáticos / Drogas Desenhadas / Indanos Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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