Gene therapy to promote regeneration in Charcot-Marie-Tooth disease.

Sahenk, Zarife; Ozes, Burcak

Sahenk, Zarife; Ozes, Burcak.

Afiliação

Sahenk Z; Center for Gene Therapy, Abigail Wexner Research Institute, Nationwide Children's Hospital, Columbus, OH, United States; Department of Pediatrics and Neurology, Nationwide Children's Hospital and The Ohio State University, United States; Department of Pathology and Laboratory Medicine, Nationwide Children's Hospital, Columbus, OH, United States; Department of Neurology, The Ohio State University, United States. Electronic address: zarife.sahenk@nationwidechildrens.org.
Ozes B; Center for Gene Therapy, Abigail Wexner Research Institute, Nationwide Children's Hospital, Columbus, OH, United States.

Brain Res ; 1727: 146533, 2020 01 15.

Article em En | MEDLINE | ID: mdl-31669284

Assuntos

Doença de Charcot-Marie-Tooth/genética; Doença de Charcot-Marie-Tooth/terapia; Terapia Genética; Fatores de Crescimento Neural/genética; Regeneração Nervosa/genética; Animais; Axônios/patologia; Doença de Charcot-Marie-Tooth/patologia; Modelos Animais de Doenças; Camundongos; Células de Schwann/patologia

Palavras-chave

CMT; Distal axonal disease; Gene therapy; Nerve regeneration; Neurotrophin 3; Schwann cell-axon interaction

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Terapia Genética / Doença de Charcot-Marie-Tooth / Fatores de Crescimento Neural / Regeneração Nervosa Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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