Dynamic Tests to Predict Fluid Responsiveness After Off-Pump Coronary Artery Bypass Grafting.
J Cardiothorac Vasc Anesth
; 34(4): 926-931, 2020 Apr.
Article
em En
| MEDLINE
| ID: mdl-31677921
ABSTRACT
OBJECTIVE:
To test the hypothesis that a positive end-expiratory pressure test and the mini-fluid challenge predict fluid responsiveness in patients after off-pump coronary artery bypass grafting.DESIGN:
Single-center pilot prospective observational study.SETTING:
City Hospital #1 of Arkhangelsk, Russian Federation.PARTICIPANTS:
Thirty-two adult patients after off-pump coronary artery surgery.INTERVENTIONS:
To assess fluid responsiveness, after arrival to the intensive care unit, all patients received a test with increase in positive end-expiratory pressure from 5 to 20 cmH2O for 2 minutes, a mini-fluid challenge test with administration of crystalloids at 1.5 mL/kg during 2 minutes, and standard fluid challenge test using 7 mL/kg during 10 minutes. MEASUREMENTS AND MAINRESULTS:
The patients with an increase in cardiac index by ≥15% after a standard fluid challenge test were defined as fluid responders. According to receiver operating characteristic analysis, a decrease in mean arterial pressure exceeding 5 mmHg in 120 seconds of the positive end-expiratory pressure test identified fluid responsiveness with an area under the curve of 0.73 (pâ¯=â¯0.03). The reduction in pulse pressure and stroke volume variations by more than 2% during mini-fluid challenge test predicted positive response to fluid load with an area under the curve of 0.77 and 0.75, respectively (p < 0.05).CONCLUSION:
Both the positive end-expiratory pressure test and the mini-fluid challenge test are feasible after off-pump coronary artery bypass grafting and can be used to predict fluid responsiveness in these patients.Palavras-chave
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Base de dados:
MEDLINE
Assunto principal:
Ponte de Artéria Coronária sem Circulação Extracorpórea
/
Hidratação
Idioma:
En
Ano de publicação:
2020
Tipo de documento:
Article