Determination of variability due to biological and technical variation in urinary extracellular vesicles as a crucial step in biomarker discovery studies.

Oeyen, Eline; Willems, Hanny; 't Kindt, Ruben; Sandra, Koen; Boonen, Kurt; Hoekx, Lucien; De Wachter, Stefan; Ameye, Filip; Mertens, Inge

Oeyen, Eline; Willems, Hanny; 't Kindt, Ruben; Sandra, Koen; Boonen, Kurt; Hoekx, Lucien; De Wachter, Stefan; Ameye, Filip; Mertens, Inge.

Afiliação

Oeyen E; Health Department, Flemish Institute for Technological Research (VITO), Mol, Belgium.
Willems H; Centre for Proteomics (CFP), University of Antwerp, Antwerp, Belgium.
't Kindt R; Health Department, Flemish Institute for Technological Research (VITO), Mol, Belgium.
Sandra K; Centre for Proteomics (CFP), University of Antwerp, Antwerp, Belgium.
Boonen K; Research Institute for Chromatography, Kortrijk, Belgium.
Hoekx L; Research Institute for Chromatography, Kortrijk, Belgium.
De Wachter S; Health Department, Flemish Institute for Technological Research (VITO), Mol, Belgium.
Ameye F; Centre for Proteomics (CFP), University of Antwerp, Antwerp, Belgium.
Mertens I; Urology Department, Antwerp University Hospital (UZA), Edegem, Belgium.

J Extracell Vesicles ; 8(1): 1676035, 2019.

Article em En | MEDLINE | ID: mdl-31681468

Palavras-chave

Extracellular vesicles; LC-MS/MS; biomarker discovery; lipidomics; power analysis; proteomics; sample size calculation; size exclusion chromatography; urine; variation

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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2019 Tipo de documento: Article