Iron potentiates microglial interleukin-1ß secretion induced by amyloid-ß.

Nnah, Israel C; Lee, Chih-Hao; Wessling-Resnick, Marianne

Nnah, Israel C; Lee, Chih-Hao; Wessling-Resnick, Marianne.

Afiliação

Nnah IC; Department of Molecular Metabolism, Harvard TH Chan School of Public Health, Boston, MA, USA.
Lee CH; Department of Molecular Metabolism, Harvard TH Chan School of Public Health, Boston, MA, USA.
Wessling-Resnick M; Department of Molecular Metabolism, Harvard TH Chan School of Public Health, Boston, MA, USA.

J Neurochem ; 154(2): 177-189, 2020 07.

Article em En | MEDLINE | ID: mdl-31693761

Assuntos

Peptídeos beta-Amiloides/farmacologia; Interleucina-1beta/biossíntese; Ferro/farmacologia; Microglia/efeitos dos fármacos; Microglia/metabolismo; Peptídeos beta-Amiloides/metabolismo; Animais; Linhagem Celular; Ferro/metabolismo; Camundongos

Palavras-chave

Alzheimer's disease; IMG (immortalized microglia) cells; divalent metal transporter-1; iron; microglia; neuroinflammation

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Peptídeos beta-Amiloides / Microglia / Interleucina-1beta / Ferro Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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