Evolutionarily conserved susceptibility of the mitochondrial respiratory chain to SDHI pesticides and its consequence on the impact of SDHIs on human cultured cells.

Bénit, Paule; Kahn, Agathe; Chretien, Dominique; Bortoli, Sylvie; Huc, Laurence; Schiff, Manuel; Gimenez-Roqueplo, Anne-Paule; Favier, Judith; Gressens, Pierre; Rak, Malgorzata; Rustin, Pierre

Bénit, Paule; Kahn, Agathe; Chretien, Dominique; Bortoli, Sylvie; Huc, Laurence; Schiff, Manuel; Gimenez-Roqueplo, Anne-Paule; Favier, Judith; Gressens, Pierre; Rak, Malgorzata; Rustin, Pierre.

Afiliação

Bénit P; Université de Paris, NeuroDiderot, INSERM, Paris, France.
Kahn A; Université de Paris, NeuroDiderot, INSERM, Paris, France.
Chretien D; Université de Paris, NeuroDiderot, INSERM, Paris, France.
Bortoli S; Université de Paris, INSERM, UMR-S 1124, Paris, France.
Huc L; INRA UMR 1331 ToxAlim (Research Center in Food Toxicology), Université de Toulouse ENVT, INP, UPS, 180 Chemin de Tournefeuille, France.
Schiff M; Université de Paris, NeuroDiderot, INSERM, Paris, France.
Gimenez-Roqueplo AP; Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Robert Debré, Service de neurologie et maladies métaboliques, Paris, France.
Favier J; Université de Paris, PARCC, INSERM, Equipe Labellisée par la Ligue contre le Cancer, Paris, France.
Gressens P; Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Européen Georges Pompidou, Service de Génétique, Paris, France.
Rak M; Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Européen Georges Pompidou, Service de Génétique, Paris, France.
Rustin P; Université de Paris, NeuroDiderot, INSERM, Paris, France.

PLoS One ; 14(11): e0224132, 2019.

Article em En | MEDLINE | ID: mdl-31697708

Assuntos

Transporte de Elétrons/efeitos dos fármacos; Praguicidas/farmacologia; Succinato Desidrogenase/antagonistas & inibidores; Animais; Antioxidantes/metabolismo; Abelhas/metabolismo; Células Cultivadas; Farmacorresistência Fúngica/efeitos dos fármacos; Proteínas Fúngicas/farmacologia; Fungos/metabolismo; Humanos; Membranas Mitocondriais/efeitos dos fármacos; Doenças Neurodegenerativas/tratamento farmacológico; Doenças Neurodegenerativas/metabolismo; Oligoquetos/metabolismo; Succinato Desidrogenase/metabolismo

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Praguicidas / Succinato Desidrogenase / Transporte de Elétrons Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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