HIF-mediated Suppression of DEPTOR Confers Resistance to mTOR Kinase Inhibition in Renal Cancer.

Doan, Hong; Parsons, Alexander; Devkumar, Shruthi; Selvarajah, Jogitha; Miralles, Francesc; Carroll, Veronica A.

Afiliação

Doan H; Vascular Biology Research Centre, Molecular and Clinical Sciences Research Institute, St George's, University of London, London SW17 0RE, UK.
Parsons A; Vascular Biology Research Centre, Molecular and Clinical Sciences Research Institute, St George's, University of London, London SW17 0RE, UK.
Devkumar S; Vascular Biology Research Centre, Molecular and Clinical Sciences Research Institute, St George's, University of London, London SW17 0RE, UK; Centre for Biomedical Education, Institute of Medical and Biomedical Education, St George's, University of London, London SW17 0RE, UK.
Selvarajah J; Vascular Biology Research Centre, Molecular and Clinical Sciences Research Institute, St George's, University of London, London SW17 0RE, UK; Centre for Biomedical Education, Institute of Medical and Biomedical Education, St George's, University of London, London SW17 0RE, UK.
Miralles F; Vascular Biology Research Centre, Molecular and Clinical Sciences Research Institute, St George's, University of London, London SW17 0RE, UK; Centre for Biomedical Education, Institute of Medical and Biomedical Education, St George's, University of London, London SW17 0RE, UK.
Carroll VA; Vascular Biology Research Centre, Molecular and Clinical Sciences Research Institute, St George's, University of London, London SW17 0RE, UK; Centre for Biomedical Education, Institute of Medical and Biomedical Education, St George's, University of London, London SW17 0RE, UK. Electronic address: vc

iScience ; 21: 509-520, 2019 Nov 22.

Article em En | MEDLINE | ID: mdl-31710966