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The peptide AC 2 isolated from Bacillus-treated Trapa japonica fruit extract rescues DHT (dihydrotestosterone)-treated human dermal papilla cells and mediates mTORC1 signaling for autophagy and apoptosis suppression.
Nam, Gun He; Jo, Kyung-Jo; Park, Ye-Seul; Kawk, Hye Won; Yoo, Je-Geun; Jang, Jin Dong; Kang, Sang Moon; Kim, Sang-Yong; Kim, Young-Min.
Afiliação
  • Nam GH; Department of Biological science and Biotechnology, College of Life science and Nano technology, Hannam University, 1646 Yuseong-daero, Yuseong-gu, Daejeon, 34054, South Korea.
  • Jo KJ; Department of Biological science and Biotechnology, College of Life science and Nano technology, Hannam University, 1646 Yuseong-daero, Yuseong-gu, Daejeon, 34054, South Korea.
  • Park YS; Department of Biological science and Biotechnology, College of Life science and Nano technology, Hannam University, 1646 Yuseong-daero, Yuseong-gu, Daejeon, 34054, South Korea.
  • Kawk HW; Department of Biological science and Biotechnology, College of Life science and Nano technology, Hannam University, 1646 Yuseong-daero, Yuseong-gu, Daejeon, 34054, South Korea.
  • Yoo JG; Department of Biological science and Biotechnology, College of Life science and Nano technology, Hannam University, 1646 Yuseong-daero, Yuseong-gu, Daejeon, 34054, South Korea.
  • Jang JD; Doori Cosmetics Co.,Ltd., 11F Galaxy Tower, 175, Saimdang-ro, Seocho-gu, Seoul, South Korea.
  • Kang SM; ANPEP INC. 13, Oksansandan 1-ro, Oksan-myeon, Heungdeok-gu, Cheongju-si, Chungcheongbuk-do, Republic of Korea.
  • Kim SY; Department of Food Science & Bio Technology, Shinansan University, Daehakro Danwon-gu, Ansan-city, Gyenggi-do, South Korea.
  • Kim YM; Department of Biological science and Biotechnology, College of Life science and Nano technology, Hannam University, 1646 Yuseong-daero, Yuseong-gu, Daejeon, 34054, South Korea. ym1938@naver.com.
Sci Rep ; 9(1): 16903, 2019 11 15.
Article em En | MEDLINE | ID: mdl-31729428
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Autofagia / Di-Hidrotestosterona / Bacillus / Extratos Vegetais / Apoptose / Folículo Piloso / Lythraceae Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Autofagia / Di-Hidrotestosterona / Bacillus / Extratos Vegetais / Apoptose / Folículo Piloso / Lythraceae Idioma: En Ano de publicação: 2019 Tipo de documento: Article