The Use of DMS-MS for the Quantitative Analysis of Acylcarnitines.
Methods Mol Biol
; 2084: 95-101, 2020.
Article
em En
| MEDLINE
| ID: mdl-31729655
ABSTRACT
Differential mobility spectrometry (DMS) is capable of separating molecules based on their size and shape. When coupled to mass spectrometry (MS), DMS reduces chemical background and enhances signal-to-noise (S/N) ratio. Flow injection analysis (FIA) is a technique used to introduce samples into the source of the DMS-MS platform. Here we describe the application of FIA-DMS-MS/MS for the analysis of urinary acylcarnitine species. More than 20 acylcarnitine species can be detected and quantified during a single FIA-DMS-MS/MS acquisition.
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Espectrometria de Massas
/
Carnitina
/
Espectrometria de Mobilidade Iônica
Idioma:
En
Ano de publicação:
2020
Tipo de documento:
Article