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Use of a physiologically-based pharmacokinetic model to explore the potential disparity in nicotine disposition between adult and adolescent nonhuman primates.
Yang, Xiaoxia; Naylor, Jennifer; Matazel, Katelin; Goodwin, Amy; Jacob, Cristina C; Bryant, Matthew; Loukotková, Lucie; Gamboa da Costa, Gonçalo; Chemerynski, Susan; Deng-Bryant, Ying; Reissig, Chad; Jackson, Kia; Fisher, Jeffrey.
Afiliação
  • Yang X; Division of Biochemical Toxicology, National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR 72079, USA. Electronic address: xiaoxia.yang@fda.hhs.gov.
  • Naylor J; Division of Neurotoxicology, National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR 72079, USA.
  • Matazel K; Division of Neurotoxicology, National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR 72079, USA.
  • Goodwin A; Division of Neurotoxicology, National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR 72079, USA.
  • Jacob CC; Division of Biochemical Toxicology, National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR 72079, USA.
  • Bryant M; Division of Biochemical Toxicology, National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR 72079, USA.
  • Loukotková L; Division of Biochemical Toxicology, National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR 72079, USA.
  • Gamboa da Costa G; Division of Biochemical Toxicology, National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR 72079, USA.
  • Chemerynski S; Division of Nonclinical Science, Center for Tobacco Products, U.S. Food and Drug Administration, Silver Spring, MD 20993, USA.
  • Deng-Bryant Y; Division of Nonclinical Science, Center for Tobacco Products, U.S. Food and Drug Administration, Silver Spring, MD 20993, USA.
  • Reissig C; Division of Individual Health Science, Center for Tobacco Products, U.S. Food and Drug Administration, Silver Spring, MD 20993, USA.
  • Jackson K; Division of Individual Health Science, Center for Tobacco Products, U.S. Food and Drug Administration, Silver Spring, MD 20993, USA.
  • Fisher J; Division of Biochemical Toxicology, National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR 72079, USA.
Toxicol Appl Pharmacol ; 386: 114826, 2020 01 01.
Article em En | MEDLINE | ID: mdl-31730783
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Nicotina Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Nicotina Idioma: En Ano de publicação: 2020 Tipo de documento: Article