The Genomic Impact of European Colonization of the Americas.
Curr Biol
; 29(23): 3974-3986.e4, 2019 12 02.
Article
em En
| MEDLINE
| ID: mdl-31735679
ABSTRACT
The human genetic diversity of the Americas has been affected by several events of gene flow that have continued since the colonial era and the Atlantic slave trade. Moreover, multiple waves of migration followed by local admixture occurred in the last two centuries, the impact of which has been largely unexplored. Here, we compiled a genome-wide dataset of â¼12,000 individuals from twelve American countries and â¼6,000 individuals from worldwide populations and applied haplotype-based methods to investigate how historical movements from outside the New World affected (1) the genetic structure, (2) the admixture profile, (3) the demographic history, and (4) sex-biased gene-flow dynamics of the Americas. We revealed a high degree of complexity underlying the genetic contribution of European and African populations in North and South America, from both geographic and temporal perspectives, identifying previously unreported sources related to Italy, the Middle East, and to specific regions of Africa.
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Base de dados:
MEDLINE
Assunto principal:
Genoma Humano
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População Negra
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Indígena Americano ou Nativo do Alasca
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População Branca
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Fluxo Gênico
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article