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5-Aminosalicylic Acid Azo-Coupled with a GPR109A Agonist Is a Colon-Targeted Anticolitic Codrug with a Reduced Risk of Skin Toxicity.
Jeong, Seongkeun; Lee, Hanju; Kim, Soojin; Ju, Sanghyun; Kim, Wooseong; Cho, Heeyeong; Kim, Hyun Young; Heo, Gwangbeom; Im, Eunok; Yoo, Jin-Wook; Yoon, In-Soo; Jung, Yunjin.
Afiliação
  • Jeong S; College of Pharmacy , Pusan National University , Busan , Republic of Korea.
  • Lee H; College of Pharmacy , Pusan National University , Busan , Republic of Korea.
  • Kim S; College of Pharmacy , Pusan National University , Busan , Republic of Korea.
  • Ju S; College of Pharmacy , Pusan National University , Busan , Republic of Korea.
  • Kim W; College of Pharmacy , Pusan National University , Busan , Republic of Korea.
  • Cho H; Biotechnology & Therapeutic Division , Korea Research Institute of Chemical Technology , Daejeon 305-343 , Republic of Korea.
  • Kim HY; Korea University of Science and Technology , 141 Gajeong-ro , Yuseong, Daejeon 305-343 , Republic of Korea.
  • Heo G; Biotechnology & Therapeutic Division , Korea Research Institute of Chemical Technology , Daejeon 305-343 , Republic of Korea.
  • Im E; College of Pharmacy , Pusan National University , Busan , Republic of Korea.
  • Yoo JW; College of Pharmacy , Pusan National University , Busan , Republic of Korea.
  • Yoon IS; College of Pharmacy , Pusan National University , Busan , Republic of Korea.
  • Jung Y; College of Pharmacy , Pusan National University , Busan , Republic of Korea.
Mol Pharm ; 17(1): 167-179, 2020 01 06.
Article em En | MEDLINE | ID: mdl-31743034
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Anti-Inflamatórios não Esteroides / Colite / Colo / Receptores Acoplados a Proteínas G Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Anti-Inflamatórios não Esteroides / Colite / Colo / Receptores Acoplados a Proteínas G Idioma: En Ano de publicação: 2020 Tipo de documento: Article