Grape Seed Polyphenols Ameliorated Dextran Sulfate Sodium-Induced Colitis via Suppression of Inflammation and Apoptosis.

Wang, Yunxia; Wang, Yunan; Shen, Wanli; Wang, Yandi; Cao, Yini; Nuerbulati, Nuerdida; Chen, Wen; Lu, Guotao; Xiao, Weiming; Qi, Rong

Wang, Yunxia; Wang, Yunan; Shen, Wanli; Wang, Yandi; Cao, Yini; Nuerbulati, Nuerdida; Chen, Wen; Lu, Guotao; Xiao, Weiming; Qi, Rong.

Afiliação

Wang Y; Peking University Institute of Cardiovascular Sciences, Peking University Health Science Center, Peking University, Beijing, China.
Wang Y; Key Laboratory of Molecular Cardiovascular Sciences, Ministry of Education, Beijing, China.
Shen W; Beijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery Systems, Beijing, China.
Wang Y; Peking University Institute of Cardiovascular Sciences, Peking University Health Science Center, Peking University, Beijing, China.
Cao Y; Key Laboratory of Molecular Cardiovascular Sciences, Ministry of Education, Beijing, China.
Nuerbulati N; School of Pharmacy, Shihezi University, Shihezi, China.
Chen W; Peking University Institute of Cardiovascular Sciences, Peking University Health Science Center, Peking University, Beijing, China.
Lu G; Key Laboratory of Molecular Cardiovascular Sciences, Ministry of Education, Beijing, China.
Xiao W; Peking University Institute of Cardiovascular Sciences, Peking University Health Science Center, Peking University, Beijing, China.
Qi R; Key Laboratory of Molecular Cardiovascular Sciences, Ministry of Education, Beijing, China.

Pharmacology ; 105(1-2): 9-18, 2020.

Article em En | MEDLINE | ID: mdl-31743904

Assuntos

Anti-Inflamatórios/uso terapêutico; Colite Ulcerativa/tratamento farmacológico; Polifenóis/uso terapêutico; Vitis; Animais; Anti-Inflamatórios/farmacologia; Apoptose/efeitos dos fármacos; Colite Ulcerativa/induzido quimicamente; Colite Ulcerativa/imunologia; Colite Ulcerativa/metabolismo; Colo/efeitos dos fármacos; Colo/patologia; Citocinas/genética; Sulfato de Dextrana; Feminino; Camundongos Endogâmicos C57BL; Polifenóis/farmacologia; RNA Mensageiro/metabolismo; Fator de Transcrição STAT3/metabolismo; Sementes

Palavras-chave

Apoptosis; Grape seed polyphenols; Inflammation; Ulcerative colitis

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Colite Ulcerativa / Vitis / Polifenóis / Anti-Inflamatórios Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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