MiR-608 Exerts Anti-inflammatory Effects by Targeting ELANE in Monocytes.

Gu, Wei; Wen, Dalin; Lu, Hongxiang; Zhang, Anqiang; Wang, Haiyan; Du, Juan; Zeng, Ling; Jiang, Jianxin

Gu, Wei; Wen, Dalin; Lu, Hongxiang; Zhang, Anqiang; Wang, Haiyan; Du, Juan; Zeng, Ling; Jiang, Jianxin.

Afiliação

Gu W; School of Medicine, Changing University, Shapingba, Chongqing, 400045, China. guwei@cqu.edu.cn.
Wen D; Key Laboratory of Biorheological Science and Technology (Chongqing University), Ministry of Education, School of Medicine, Chongqing University, Shapingba, Chongqing, 400045, China.
Lu H; State Key Laboratory of Trauma, Burns and Combined Injury, Institute of Surgery Research, Daping Hospital, Army Medical University, Daping, Chongqing, 400042, China.
Zhang A; State Key Laboratory of Trauma, Burns and Combined Injury, Institute of Surgery Research, Daping Hospital, Army Medical University, Daping, Chongqing, 400042, China.
Wang H; State Key Laboratory of Trauma, Burns and Combined Injury, Institute of Surgery Research, Daping Hospital, Army Medical University, Daping, Chongqing, 400042, China.
Du J; State Key Laboratory of Trauma, Burns and Combined Injury, Institute of Surgery Research, Daping Hospital, Army Medical University, Daping, Chongqing, 400042, China.
Zeng L; State Key Laboratory of Trauma, Burns and Combined Injury, Institute of Surgery Research, Daping Hospital, Army Medical University, Daping, Chongqing, 400042, China.
Jiang J; State Key Laboratory of Trauma, Burns and Combined Injury, Institute of Surgery Research, Daping Hospital, Army Medical University, Daping, Chongqing, 400042, China.

J Clin Immunol ; 40(1): 147-157, 2020 01.

Article em En | MEDLINE | ID: mdl-31749032

Assuntos

Anti-Inflamatórios/metabolismo; Inflamação/metabolismo; Elastase de Leucócito/metabolismo; MicroRNAs/metabolismo; Monócitos/metabolismo; Adulto; Linhagem Celular; Linhagem Celular Tumoral; Regulação para Baixo/fisiologia; Perfilação da Expressão Gênica/métodos; Regulação da Expressão Gênica/fisiologia; Células HEK293; Humanos; RNA Mensageiro/metabolismo; Transdução de Sinais/fisiologia; Células THP-1; Células U937; Regulação para Cima/fisiologia; Adulto Jovem

Palavras-chave

ELANE; Sepsis; miR-608; microRNAs; microarray

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Monócitos / Elastase de Leucócito / MicroRNAs / Inflamação / Anti-Inflamatórios Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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