Efficacy of Retinal Lesion Screening in Von Hippel-Lindau Patients With Widefield Color Fundus Imaging Versus Widefield FA.
Ophthalmic Surg Lasers Imaging Retina
; 50(11): e260-e265, 2019 11 01.
Article
em En
| MEDLINE
| ID: mdl-31755976
ABSTRACT
BACKGROUND AND OBJECTIVE:
Retinal hemangioblastoma is a retinal tumor in patients with Von Hippel-Lindau (VHL). The authors' objective was to determine whether widefield fluorescein angiography (FA) improves lesion detection. PATIENTS ANDMETHODS:
Retrospective case series of VHL patients who underwent widefield fundus imaging and FA. Masked retina specialists graded fundus images as having 1) definite retinal hemangioblastoma; 2) possible lesion; 3) no lesion. The number of lesions on FA was compared to widefield color imaging.RESULTS:
One hundred six eyes of 55 patients were evaluated. A total of 94 lesions were identified on FA in 61.8% patients. Forty-three lesions (45.7%) were not identified on fundus images. Small lesion detection was significantly higher with FA compared to color imaging (P = .013).CONCLUSIONS:
This study reports on improved detection of retinal hemangioblastomas with widefield FA compared to widefield fundus images. The authors recommend VHL monitoring guidelines to include periodic widefield FA to adequately screen for smaller lesions. [Ophthalmic Surg Lasers Imaging Retina. 2019;50e260-e265.].
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Angiofluoresceinografia
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Hemangioblastoma
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Neoplasias da Retina
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Doença de von Hippel-Lindau
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article