Stigmasterol stimulates transintestinal cholesterol excretion independent of liver X receptor activation in the small intestine.

Lifsey, Hannah C; Kaur, Rupinder; Thompson, Bradley H; Bennett, Lisa; Temel, Ryan E; Graf, Gregory A

Lifsey, Hannah C; Kaur, Rupinder; Thompson, Bradley H; Bennett, Lisa; Temel, Ryan E; Graf, Gregory A.

Afiliação

Lifsey HC; Department of Pharmaceutical Sciences, College of Pharmacy.
Kaur R; Department of Pharmaceutical Sciences, College of Pharmacy.
Thompson BH; Department of Pharmaceutical Sciences, College of Pharmacy.
Bennett L; Department of Pharmaceutical Sciences, College of Pharmacy.
Temel RE; Department of Physiology, College of Medicine, University of Kentucky; Saha Cardiovascular Research Center.
Graf GA; Department of Pharmaceutical Sciences, College of Pharmacy; Saha Cardiovascular Research Center; Barnstable Brown Diabetes and Obesity Center. Electronic address: Gregory.Graf@UKY.edu.

J Nutr Biochem ; 76: 108263, 2020 02.

Article em En | MEDLINE | ID: mdl-31759199

Assuntos

Colesterol/metabolismo; Intestino Delgado/efeitos dos fármacos; Receptores X do Fígado/metabolismo; Estigmasterol/farmacologia; Animais; Aterosclerose/metabolismo; Bile/metabolismo; Ductos Biliares/metabolismo; Feminino; Hidrocarbonetos Fluorados/farmacologia; Intestino Delgado/metabolismo; Fígado/metabolismo; Masculino; Camundongos; Camundongos Endogâmicos C57BL; Receptores Nucleares Órfãos/metabolismo; Fitosteróis/metabolismo; Esteróis/metabolismo; Sulfonamidas/farmacologia

Palavras-chave

Bile; Cholesterol; LXR; Phytosterol; TICE

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Estigmasterol / Colesterol / Receptores X do Fígado / Intestino Delgado Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google