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A functionalized hydroxydopamine quinone links thiol modification to neuronal cell death.
Farzam, Ali; Chohan, Karan; Strmiskova, Miroslava; Hewitt, Sarah J; Park, David S; Pezacki, John P; Özcelik, Dennis.
Afiliação
  • Farzam A; Department of Chemistry and Biomolecular Sciences, University of Ottawa, 10 Marie Curie Private, Ottawa, ON, K1N 6N5, Canada.
  • Chohan K; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, 451 Smyth Road, Ottawa, ON, K1H 8M5, Canada.
  • Strmiskova M; Department of Chemistry and Biomolecular Sciences, University of Ottawa, 10 Marie Curie Private, Ottawa, ON, K1N 6N5, Canada.
  • Hewitt SJ; University of Ottawa Brain and Mind Research Institute, Department of Cellular and Molecular Medicine, University of Ottawa, 451 Smyth Road, Ottawa, ON, K1H 8M5, Canada.
  • Park DS; University of Ottawa Brain and Mind Research Institute, Department of Cellular and Molecular Medicine, University of Ottawa, 451 Smyth Road, Ottawa, ON, K1H 8M5, Canada.
  • Pezacki JP; Department of Chemistry and Biomolecular Sciences, University of Ottawa, 10 Marie Curie Private, Ottawa, ON, K1N 6N5, Canada; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, 451 Smyth Road, Ottawa, ON, K1H 8M5, Canada.
  • Özcelik D; Department of Chemistry and Biomolecular Sciences, University of Ottawa, 10 Marie Curie Private, Ottawa, ON, K1N 6N5, Canada. Electronic address: dennis.ozcelik@sund.ku.dk.
Redox Biol ; 28: 101377, 2020 01.
Article em En | MEDLINE | ID: mdl-31760358
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença de Parkinson / Compostos de Sulfidrila / Isomerases de Dissulfetos de Proteínas / Neurônios Dopaminérgicos / Hidroxidopaminas Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença de Parkinson / Compostos de Sulfidrila / Isomerases de Dissulfetos de Proteínas / Neurônios Dopaminérgicos / Hidroxidopaminas Idioma: En Ano de publicação: 2020 Tipo de documento: Article