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Discovery of an antivirulence compound that reverses ß-lactam resistance in MRSA.
El-Halfawy, Omar M; Czarny, Tomasz L; Flannagan, Ronald S; Day, Jonathan; Bozelli, José Carlos; Kuiack, Robert C; Salim, Ahmed; Eckert, Philip; Epand, Richard M; McGavin, Martin J; Organ, Michael G; Heinrichs, David E; Brown, Eric D.
Afiliação
  • El-Halfawy OM; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada.
  • Czarny TL; Michael G. DeGroote Institute of Infectious Disease Research, McMaster University, Hamilton, Ontario, Canada.
  • Flannagan RS; Microbiology and Immunology Department, Faculty of Pharmacy, Alexandria University, Alexandria, Egypt.
  • Day J; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada.
  • Bozelli JC; Michael G. DeGroote Institute of Infectious Disease Research, McMaster University, Hamilton, Ontario, Canada.
  • Kuiack RC; Department of Microbiology and Immunology, The University of Western Ontario, London, Ontario, Canada.
  • Salim A; Department of Chemistry, York University, Toronto, Ontario, Canada.
  • Eckert P; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada.
  • Epand RM; Department of Microbiology and Immunology, The University of Western Ontario, London, Ontario, Canada.
  • McGavin MJ; Department of Chemistry, York University, Toronto, Ontario, Canada.
  • Organ MG; Centre for Catalysis Research and Innovation (CCRI) and Department of Chemistry and Biomolecular Sciences, University of Ottawa, Ottawa, Ontario, Canada.
  • Heinrichs DE; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada.
  • Brown ED; Department of Microbiology and Immunology, The University of Western Ontario, London, Ontario, Canada.
Nat Chem Biol ; 16(2): 143-149, 2020 02.
Article em En | MEDLINE | ID: mdl-31768032
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Piperidinas / Piridinas / Resistência beta-Lactâmica / Staphylococcus aureus Resistente à Meticilina / Ensaios de Triagem em Larga Escala / Antibacterianos Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Piperidinas / Piridinas / Resistência beta-Lactâmica / Staphylococcus aureus Resistente à Meticilina / Ensaios de Triagem em Larga Escala / Antibacterianos Idioma: En Ano de publicação: 2020 Tipo de documento: Article