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Robust Optimization for Intensity Modulated Proton Therapy Plans with Multi-Isocenter Large Fields.
Liao, Li; Lim, Gino J; Li, Yupeng; Yu, Juan; Sahoo, Narayan; Li, Heng; Gillin, Michael; Zhu, X Ronald; Mahajan, Anita; Frank, Steven J; Grosshans, David R; Nguyen, Quynh-Nhu; Gomez, Daniel; Zhang, Xiaodong.
Afiliação
  • Liao L; Department of Industrial Engineering, The University of Houston, Houston, TX, USA.
  • Lim GJ; Department of Industrial Engineering, The University of Houston, Houston, TX, USA.
  • Li Y; Applied Research, Varian Medical Systems, Palo Alto, CA, USA.
  • Yu J; Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Sahoo N; Maryland Proton Treatment Center, Department of Radiation Oncology, University of Maryland School of Medicine, Baltimore, MD, USA.
  • Li H; Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Gillin M; Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Zhu XR; Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Mahajan A; Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Frank SJ; Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Grosshans DR; Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Nguyen QN; Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Gomez D; Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Zhang X; Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Int J Part Ther ; 3(2): 305-311, 2016.
Article em En | MEDLINE | ID: mdl-31772982
ABSTRACT
We have developed a robust optimization approach for intensity modulated proton therapy treatment plans with multi-isocenter large fields. The method creates a low-gradient field dose in the junction regions to mitigate the impact caused by misalignment errors and is more efficient than the conventional junction shifting technique.
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2016 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2016 Tipo de documento: Article