B1 and Marginal Zone B Cells but Not Follicular B2 Cells Require Gpx4 to Prevent Lipid Peroxidation and Ferroptosis.

Muri, Jonathan; Thut, Helen; Bornkamm, Georg W; Kopf, Manfred

Muri, Jonathan; Thut, Helen; Bornkamm, Georg W; Kopf, Manfred.

Afiliação

Muri J; Institute of Molecular Health Sciences, ETH Zurich, 8093 Zürich, Switzerland.
Thut H; Institute of Molecular Health Sciences, ETH Zurich, 8093 Zürich, Switzerland.
Bornkamm GW; Institute of Clinical Molecular Biology and Tumor Genetics, Helmholtz Zentrum München, 85764 Neuherberg, Germany.
Kopf M; Institute of Molecular Health Sciences, ETH Zurich, 8093 Zürich, Switzerland. Electronic address: manfred.kopf@ethz.ch.

Cell Rep ; 29(9): 2731-2744.e4, 2019 Nov 26.

Article em En | MEDLINE | ID: mdl-31775041

Assuntos

Linfócitos B/metabolismo; Proteínas do Citoesqueleto/metabolismo; Ferroptose/efeitos dos fármacos; Glutationa Peroxidase/uso terapêutico; Peroxidação de Lipídeos/efeitos dos fármacos; Humanos

Palavras-chave

B cell immunometabolism; B1 cells; Gpx4; fatty-acid metabolism; ferroptosis; glutathione; lipid ROS; marginal zone B cells; redox system

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Linfócitos B / Peroxidação de Lipídeos / Proteínas do Citoesqueleto / Ferroptose / Glutationa Peroxidase Idioma: En Ano de publicação: 2019 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google