Toll-Like Receptor Mediated Activation of Natural Autoantibody Producing B Cell Subpopulations in an Autoimmune Disease Model.

Erdo-Bonyár, Szabina; Rapp, Judit; Minier, Tünde; Ráth, Gábor; Najbauer, József; Czirják, László; Németh, Péter; Berki, Timea; Simon, Diána

Erdo-Bonyár, Szabina; Rapp, Judit; Minier, Tünde; Ráth, Gábor; Najbauer, József; Czirják, László; Németh, Péter; Berki, Timea; Simon, Diána.

Afiliação

Erdo-Bonyár S; Department of Immunology and Biotechnology, Clinical Center, University of Pécs Medical School, H-7624 Pécs, Hungary.
Rapp J; Department of Rheumatology and Immunology, Clinical Center, University of Pécs Medical School, H-7632 Pécs, Hungary.
Minier T; Department of Immunology and Biotechnology, Clinical Center, University of Pécs Medical School, H-7624 Pécs, Hungary.
Ráth G; Department of Rheumatology and Immunology, Clinical Center, University of Pécs Medical School, H-7632 Pécs, Hungary.
Najbauer J; Department of Pediatrics, Clinical Center, University of Pécs Medical School, H-7623 Pécs, Hungary.
Czirják L; Department of Immunology and Biotechnology, Clinical Center, University of Pécs Medical School, H-7624 Pécs, Hungary.
Németh P; Department of Rheumatology and Immunology, Clinical Center, University of Pécs Medical School, H-7632 Pécs, Hungary.
Berki T; Department of Immunology and Biotechnology, Clinical Center, University of Pécs Medical School, H-7624 Pécs, Hungary.
Simon D; Department of Immunology and Biotechnology, Clinical Center, University of Pécs Medical School, H-7624 Pécs, Hungary.

Int J Mol Sci ; 20(24)2019 Dec 06.

Article em En | MEDLINE | ID: mdl-31817576

Assuntos

Doenças Autoimunes/metabolismo; Subpopulações de Linfócitos B/metabolismo; Linfócitos B/metabolismo; Receptores Toll-Like/metabolismo; Adolescente; Adulto; Idoso; Antígenos CD/metabolismo; Antígenos CD19/metabolismo; Citrato (si)-Sintase/metabolismo; DNA Topoisomerases Tipo I/metabolismo; Feminino; Humanos; Interleucina-10/metabolismo; Interleucina-6/metabolismo; Ativação Linfocitária/fisiologia; Masculino; Pessoa de Meia-Idade; Adulto Jovem

Palavras-chave

B cells; CD180; CpG; DNA topoisomerase I; IL-10; IL-6; IgM; RP105; TLR; citrate synthase; dcSSc; natural autoantibodies; non-switched B cells; systemic sclerosis

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doenças Autoimunes / Linfócitos B / Subpopulações de Linfócitos B / Receptores Toll-Like Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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