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Visual Acuity Outcome over Time in Non-Infectious Uveitis.
Pistilli, Maxwell; Joffe, Marshall M; Gangaputra, Sapna S; Pujari, Siddharth S; Jabs, Douglas A; Levy-Clarke, Grace A; Nussenblatt, Robert B; Rosenbaum, James T; Sen, H Nida; Suhler, Eric B; Thorne, Jennifer E; Bhatt, Nirali P; Foster, C Stephen; Begum, Hosne; Fitzgerald, Tonetta D; Dreger, Kurt A; Altaweel, Michael M; Holbrook, Janet T; Kempen, John H.
Afiliação
  • Pistilli M; The Scheie Eye Institute, The University of Pennsylvania School of Medicine, Philadelphia, PA, USA.
  • Joffe MM; The Center for Preventive Ophthalmology and Biostatistics, Department of Ophthalmology, The University of Pennsylvania School of Medicine, Philadelphia, PA, USA.
  • Gangaputra SS; The Center for Clinical Epidemiology and Biostatistics, Department of Biostatistics and Epidemiology, The University of Pennsylvania School of Medicine, Philadelphia, PA, USA.
  • Pujari SS; Department of Ophthalmology and Vision Sciences, Vanderbilt Eye Institute, Nashville, TN, USA.
  • Jabs DA; Om Eye Care Hospital, Belgaum, India.
  • Levy-Clarke GA; Department of Epidemiology, The Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA.
  • Nussenblatt RB; Departments of Ophthalmology and Medicine, The Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Rosenbaum JT; Laboratory of Immunology, National Eye Institute, Bethesda, MD, USA.
  • Sen HN; Tampa Bay Uveitis Center, Tampa, FL, USA.
  • Suhler EB; Department of Ophthalmology, Oregon Health and Science University, Portland, OR, USA.
  • Thorne JE; Laboratory of Immunology, National Eye Institute, Bethesda, MD, USA.
  • Bhatt NP; Department of Ophthalmology, Oregon Health and Science University, Portland, OR, USA.
  • Foster CS; Department of Medicine, Oregon Health and Science University, Portland, OR, USA.
  • Begum H; Laboratory of Immunology, National Eye Institute, Bethesda, MD, USA.
  • Fitzgerald TD; Department of Ophthalmology, Oregon Health and Science University, Portland, OR, USA.
  • Dreger KA; Department of Medicine, Oregon Health and Science University, Portland, OR, USA.
  • Altaweel MM; Ophthalmology Service, Portland Veteran's Affairs Medical Center, Portland, OR, USA.
  • Holbrook JT; Department of Epidemiology, The Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA.
  • Kempen JH; Department of Ophthalmology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Ocul Immunol Inflamm ; 29(6): 1064-1071, 2021 Aug 18.
Article em En | MEDLINE | ID: mdl-31821051
Introduction: We evaluated visual acuity (VA) over 5 years in a subspecialty noninfectious uveitis population.Methods: Retrospective data from 5,530 noninfectious uveitis patients with anterior, intermediate, posterior or panuveitis were abstracted by expert reviewers. Mean VA was calculated using inverse probability of censoring weighting to account for losses to follow-up.Results: Patients were a median of 41 years old, 65% female, and 73% white. Initial mean VA was worse among panuveitis (20/84) than posterior (20/64), intermediate (20/47), and anterior (20/37) uveitides. On average, mean VA improved by 0.62, 0.51, 0.37, and 0.26 logMAR-equivalent lines over 2 years, respectively (each P < .001), then remained stable, except posterior uveitis mean VA worsened to initial levels.Conclusion: Mean VA of uveitic eyes improved and, typically, improvement was sustained under uveitis subspecialty care. Because VA tends to improve under tertiary care, mean VA change appears a better outcome for clinical studies than time-to-loss of VA.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Uveíte / Acuidade Visual Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Uveíte / Acuidade Visual Idioma: En Ano de publicação: 2021 Tipo de documento: Article